Results 51 to 60 of about 781,615 (301)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Diachronic and/or synchronic variation? The acquisition of sociolinguistic competence in L2 French. [PDF]
, 2007 A majority of the early research in Second Language Acquisition focused on diachronic variation in the learners’ interlanguage (IL), that is, differences in the IL linked to a supposed increase in knowledge between two points in time (cf.
Dewaele, Jean-Marc
core
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Slavistica Vilnensis, 2011 Konstantin V. Lifanov From the History of Formation of the Slovak Literary Language: A. Bernolák’s Codification and Norm Formation in Texts of Bernolák’s Supporters A. Rudnay and Fr.K.
Константин Васильевич Лифанов
doaj +1 more source
Some Observations for Mean-Field Spin Glass Models
, 2007 We obtain bounds to show that the pressure of a two-body, mean-field spin glass is a Lipschitz function of the underlying distribution of the random coupling constants, with respect to a particular semi-norm.
Brigitta Vermesi +4 more
core +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Limits of the Comical and Language Game [PDF]
, 2018 Статья посвящена изучению пределов комичного и их связи с языковой игрой. Анализ положений философских, эстетических и языковых концепций показывает, что ученые признают связь комизма с нарушением нормы, но не могут объяснить, почему нарушение нормы не ...
Popov, Sergey
core +3 more sources
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Вызовы современному русскому литературному языку
Studia Rossica Posnaniensia, 2020 The article is devoted to the study of some active processes affecting the system of the modern Russian language. The result of the study is the identification of factors that negatively affect the dynamics of the Russian language, which are presented in
Владимир Медведев
doaj +1 more source