Results 91 to 100 of about 6,526,484 (245)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

VoicePAT: An Efficient Open-Source Evaluation Toolkit for Voice Privacy Research

IEEE Open Journal of Signal Processing
Speaker anonymization is the task of modifying a speech recording such that the original speaker cannot be identified anymore. Since the first Voice Privacy Challenge in 2020, along with the release of a framework, the popularity of this research topic ...
Sarina Meyer, Xiaoxiao Miao, Ngoc Thang Vu   +2 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Multiword expressions in Natural Language Processing: Current trends and challenges

The present volume addresses the way in which multiword expression resources are used in real-life downstream Natural Language Processing applications, how they interact with neural architectures and generative pre-trained language models and, more ...
Makhachashvili, Rusudan, Mitrofan, Maria, Amaro, Raquel, Păiș, Vasile, Mamede, Nuno, Überrück-Fries, Till, Liebeskind, Chaya, Dryjańska, Agnieszka, Markovic, Alexandra, Fotopoulou, Aggeliki, Payne, Amanda, Bonn, Julia, Savary, Agata, Baptista, Jorge, Koeva, Svetla, Antunes, David, Korvel, Gražina, Kyriazi, Panagiota, Bonial, Claire, Vacalopoulou, Anna, Nousias, Stavros, Lu, Chris, Stoyanova, Ivelina, Ribeiro, Eugénio, Mork, James, Barbu Mititelu, Verginica, Lobzhanidze, Irina, Markantonatou, Stella, Valunaite Oleskeviciene, Giedre, Giouli, Voula, Tayyar Madabushi, Harish   +30 more
core   +2 more sources

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Knowledge Base Question Answering With Attentive Pooling for Question Representation

IEEE Access, 2019
This paper presents a neural network model for a knowledge base (KB)-based single-relation question answering (SR-QA). This model is composed of two main modules, i.e., entity linking and relation detection.
Run-Ze Wang, Zhen-Hua Ling, Yu Hu
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

MCP-X: An Ultra-Compact CNN for Rice Disease Classification in Resource-Constrained Environments

AgriEngineering
Rice, a dietary staple for over half of the global population, is highly susceptible to bacterial and fungal diseases such as bacterial blight, brown spot, and leaf smut, which can severely reduce yields.
Xiang Zhang, Lining Yan, Belal Abuhaija, Baha Ihnaini   +3 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source