Results 51 to 60 of about 31,056,736 (269)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Exploring higher order thinking skills (HOTs) through lecturers’ beliefs and practices in teaching speaking skills

open access: yesDiscover Education
Fostering HOTS in speaking instruction is increasingly recognized as essential for developing students’ communicative and critical thinking capacities. However, research examining how HOTS is understood and enacted in speaking instruction, particularly ...
Syilvia Mustanuri Jannah   +2 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Thought and Language in Cognitive Science

open access: yesRevista Argentina de Ciencias del Comportamiento, 2012
In cognitive science, the discussion about the relations between language and thought is very heterogeneous. It involves developments on linguistics, philosophy, psychology, etc.
Destéfano, Mariela
doaj  

Fostering EFL Students' Pragmatic Competence Through Flipped-STAD Learning: A Study of ELT in an Islamic Higher Education Context

open access: yesRegister Journal
This study investigated the impact of integrating Flipped Learning (FL) and Student Team Achievement Division (STAD) on the pragmatic competence of English as Foreign Language (EFL) students, with a particular focus on their pragmalinguistic competence ...
Pipit Muliyah   +5 more
doaj   +1 more source

Towards a new biological science of language

open access: yesMètode Science Studies Journal: Annual Review, 2018
Science is the human activity aimed at acquiring knowledge by means of a very specific method, the scientific method, in which logical reasoning is put at the service of empirical and observable evidence. We perfectly understand what it means to be able
Jaume Bertranpetit
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Neural correlates of semantic-driven syntactic parsing in sentence comprehension

open access: yesNeuroImage
For sentence comprehension, information carried by semantic relations between constituents must be combined with other information to decode the constituent structure of a sentence, due to atypical and noisy situations of language use.
Yun Zhang   +3 more
doaj   +1 more source

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