Results 61 to 70 of about 383,948 (244)

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz, Ryan Cooper, Stefania Kaninia, Kathryn I. Challis, Will Greenway, Maria Bonello, Mahmoud Elbahnasawi, Deborah T. Shode, Dominika Gajdasik, Victor Iliev, Alison M. E. Whitelegg, Ian Galea   +11 more
wiley   +1 more source

Morphological priming during language switching: an ERP study

Frontiers in Human Neuroscience, 2014
Bilingual language control (BLC) is a much-debated issue in recent literature. Some models assume BLC is achieved by various types of inhibition of the non-target language, whereas other models do not assume any inhibitory mechanisms.
Saskia E. Lensink, Saskia E. Lensink, Rinus G. Verdonschot, Rinus G. Verdonschot, Niels O Schiller, Niels O Schiller   +5 more
doaj   +1 more source

Trilingual conversations: a window into multicompetence [PDF]

, 2007
A recurrent theme in the literature on trilingual language use is the question of whether there is a specific “trilingual competence.” In this paper we consider this question in the light of codeswitching patterns in two dyadic trilingual conversations ...
Baetens Beardsmore, H., Cenoz, J., Cenoz, J., Cook, V., Dewaele, J.-M., Gardner-Chloros, P., Hoffmann, C., Hoffmann, C., Jean-Marc Dewaele, Labrie, N., Malcolm Edwards, Myers-Scotton, C., Ringbom, H.   +12 more
core   +1 more source

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane, Giorgia Coratti, Chiara Cutrì, Antonio Varone, Riccardo Masson, Adele D'Amico, Valeria Sansone, Sonia Messina, Federica Ricci, Chiara Ticci, Claudio Bruno, Caterina Agosto, Francesca Benedetti, Antonella Pini, Sabrina Siliquini, Massimiliano Filosto, Alberto Zambon, Ilaria Bitetti, Maria Rosaria Manna, Claudia Dosi, Riccardo Zanin, Stefano Parravicini, Roberto De Sanctis, Giulia Stanca, Michela Catteruccia, Michele Tosi, Irene Mizzoni, Emilio Albamonte, Valentina Franchino, Maria Sframeli, Ilaria Cavallina, Elena Procopio, Michele Sacchini, Simone Morando, Noemi Brolatti, Federica Trucco, Gaia Scarpini, Elena Briganti, Beatrice Berti, Concetta Palermo, Daniela Leone, Stefano C. Previtali, Eugenio Mercuri, the ITASMAC working group   +43 more
wiley   +1 more source

Language control is not a one-size-fits-all languages process: Evidence from simultaneous interpretation students and the n-2 repetition cost

Frontiers in Psychology, 2015
Simultaneous interpretation is an impressive cognitive feat which necessitates the simultaneous use of two languages and therefore begs the question: how is language management accomplished during interpretation?
Laura eBabcock, Antonino eVallesi
doaj   +1 more source

Cognitive cost of switching between standard and dialect varieties [PDF]

, 2014
Switching between languages in picture naming incurs a cost associated with inhibition of the non-target language (Meuter & Allport, 1999).This cost is symmetrical in balanced bilinguals and asymmetrical in unbalanced bilinguals with higher cost ...
Declerck, Mathieu, Kempe, Vera, Kirk, Neil, Philipp, Andrea, Scott-Brown, Kenneth C.   +4 more
core  

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Linking Context to Language Switching: Effects of Background Noise on Bilingual Language Comprehension

Behavioral Sciences
In the present study, we set out to examine the effect of background noise on bilingual language comprehension between a person’s first language (L1) and second language (L2).
Lu Jiao, Zejun Wang, Xiaoting Duan, Yingying Yu, Cong Liu   +4 more
doaj   +1 more source

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

Annals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold, Krzysztof W. Selmaj, Regina Berkovich, Jeffrey A. Cohen, Giancarlo Comi, Eva K. Havrdová, James K. Sheffield, Hetal Desai, Chun‐Yen Cheng, Jon V. Riolo, Andrew Thorpe, Erik DeBoer, Bruce A. C. Cree   +12 more
wiley   +1 more source

Cognitive and Linguistic Predictors of Language Control in Bilingual Children

Frontiers in Psychology, 2020
In order to communicate effectively with a variety of conversation partners and in a variety of settings, bilingual children must develop language control, the ability to control which language is used for production.
Megan C. Gross, Margarita Kaushanskaya
doaj   +1 more source