Results 101 to 110 of about 1,340,612 (290)

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

The language backfire effect: do customers always prefer to be served in their strongest language? [PDF]

, 2013
Current research in service research and sociolinguistics proposes that customers who are served in their native language hold more favorable impressions of the service provider than customers served in their second language.
Dahlèn, Micael, Holmqvist, Jonas, Van Vaerenbergh, Yves   +2 more
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Alih Kode dan Campur Kode pada Akun Instagram @Londokampung: Kajian Sosiolinguistik

Edukasia
This research aims to explore the forms of language variants in the form of types of sociolect, diction, code switching and code mixing which is used on the Instagram account @Londokampung.
Yuni Arta Yuda Wicaksana, Udjang Pairin M. Basir, Yuniseffendri Yuniseffendri   +2 more
doaj   +1 more source

SEXISM AND VARIATIONS IN THE USE OF LANGUAGE. [PDF]

International Journal of Advanced Research, 2017
This paper tries to focus on the use of language of men and women through concentrating on sexism and variations. In this paper, the research tends to make an attempt to explore, examine and evaluate the difference in language choice from different students of universities situated at Dhaka city.
openaire   +2 more sources

A modernized PDL approach for Ada software development [PDF]

The desire to integrate newly available, graphically-oriented Computed Aided Software Engineering (CASE) tools with existing software design approaches is changing the way Program Design Language (PDL) or Process Description Language is used for large ...
Usavage, Paul, Jr.
core   +1 more source

Three form potential in (special) minimal supergravity superspace and supermembrane supercurrent

, 2011
This contribution begins the study of the complete superfield Lagrangian description of the interacting system of D=4 N=1 supergravity (SUGRA) and supermembrane. Firstly, we review a 'three form supergravity' by Ovrut and Waldram, which we prefer to call
Alvarez E, Alvarez E, Bagger J, Bandos I A, Bergshoeff E, Butter D, Carlos Meliveo, Dumitrescu T T, Festuccia G, Gates S J, Huebscher M, Igor A Bandos, Ivanov E A, Ivanov E A, Komargodski Z, Komargodski Z, Komargodski Z, Komargodski Z, Kuzenko S M, Kuzenko S M, Kuzenko S M, Kuzenko S M, L Alvarez-Gaume, Ogievetski V I, Ogievetsky V I, Ogievetsky V I, Ogievetsky V I, Siegel W, Townsend P K, Volkov D V, Wess J, Wess J   +31 more
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Scientific conference englishes : epistemic and language community variations [PDF]

, 2005
International audienceThe two aspects we will focus on are speakers' organisational and interactional strategies. A conference presentation is an extended monologue of informational discourse, with a logical hierarchical structure.
Carter-Thomas, Shirley, Rowley-Jolivet, Elizabeth   +1 more
core   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source