Results 91 to 100 of about 23,632 (261)

The sociolinguistic foundations of language modeling

Frontiers in Artificial Intelligence
In this article, we introduce a sociolinguistic perspective on language modeling. We claim that language models in general are inherently modeling varieties of language, and we consider how this insight can inform the development and deployment of ...
Jack Grieve, Sara Bartl, Matteo Fuoli, Jason Grafmiller, Weihang Huang, Alejandro Jawerbaum, Akira Murakami, Marcus Perlman, Dana Roemling, Bodo Winter   +9 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

LANGUAGE CHANGES, APPROXIMATIVE VARIETIES AND TRANSLATION

Belas Infiéis, 2016
From the media and communicative demands in a globalized context comes the need of using loan words for interaction and entertainment purposes. Using approximative varieties makes the languages to diachronically undergo changes in their syntactic ...
Sabine Gorovitz , Leonardo Martins Lopes
doaj  

Language and varieties

Al-Mukhtar Journal of Social Sciences
تستكشف هذه الدراسة العلاقة بين اللغة وتنوع اللهجات، مع التركيز على اكتساب اللغة بشكل غير مدرك خلال الطفولة المبكرة. تناقش الدراسة الاختلافات بين اللغة الرسمية واللهجات، وطبيعة التغيرات اللغوية، ونموذج شجرة العائلة لتغيير اللغة، ومفهوم السجلات اللغوية، والتمييز بين اللغة المنطوقة والمكتوبة. 
openaire   +1 more source

Threonine 348 regulates the subcellular localization of PTEN

FEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

A case study of three Chinese-Spanish varieties: Tense-Aspect morphology in instructed and non-instructed language use

Journal of Ibero-Romance Creoles, 2018
Researchers in second language acquisition (SLA) have examined the acquisition and use of tense-aspect (TA) morphology in predominantly tutored, second language (L2) varieties (Andersen & Shirai 1996; Bardovi-Harlig 1998; Quesada 2013; Salaberry 2005 ...
Travis Evans-Sago
doaj  

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source