Results 91 to 100 of about 9,903 (310)

英語教員の学びにおけるピアインターアクションの役割 ―模擬授業と事後ディスカッションを通じた意味生成― [PDF]

open access: yes, 2018
次期学習指導要領では「主体的・対話的で深い学び」が核となっている(文部科学省, 2016)が、こうした学びを実現するには、まず教師自身がそれを経験しておくことが重要であると言える。本研究では、英語を指導言語とする大学院の授業で、現職教員が行う模擬授業とその振り返りに焦点を当てる。社会文化理論 (Vygotsky, 1978)の立場から、学びを社会的相互交流に媒介されるものと捉え、模擬授業と事後ディカッションにおけるピアインターアクションを通じた主要参加者の「意味生成の軌跡」(Twiner ...
小林, 恵美, 小林, 真記
core  

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

‘This you may NNNNNNEVER have heard before’: initial lengthening of accented negative items as vocal-entangled gestures

open access: yesLanguage and Cognition
Movement scientists have proposed to ground the relation between prosody and gesture in ‘vocal-entangled gestures’, defined as biomechanical linkages between upper limb movement and the respiratory–vocal system. Focusing on spoken language negation, this
Simon Harrison
doaj   +1 more source

Multimodal Languaging as a Pedagogical Model—A Case Study of the Concept of Division in School Mathematics

open access: yesEducation Sciences, 2017
The purpose of this study is to present a multimodal languaging model for mathematics education. The model consists of mathematical symbolic language, a pictorial language, and a natural language.
Jorma Joutsenlahti, Pirjo Kulju
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Ecolinguistics: A paradigm shift

open access: yesRussian Journal of Linguistics
Unlike other modern sciences that have dramatically transformed our way of life over a historically short period of time, linguistics cannot boast of any serious achievements that affect our daily life. This raises the issue of practicality of linguistic
Alexander V. Kravchenko
doaj   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Post-modern ‘languagers’: the effects of texting by university students on three South African languages [PDF]

open access: yes, 2015
The present post-modern society has witnessed a growth spurt in technology, and with the development of Information and Communication Technologies (ICTs), mobile text messaging (texting) is now seen as the norm among the youth.
Bakhtin M.   +13 more
core   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

(Trans)languaging-for-learning: A perspective from the South

open access: yesReading & Writing
Background: While the concept of translanguaging has gained significant traction in education in multilingual contexts, it is also debated and contested.
Carolyn McKinney, Robyn Tyler
doaj   +1 more source

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