Results 21 to 30 of about 322,606 (297)

UBQLN1 mediates sorafenib resistance through regulating mitochondrial biogenesis and ROS homeostasis by targeting PGC1β in hepatocellular carcinoma

Signal Transduction and Targeted Therapy, 2021
The treatment for hepatocellular carcinoma (HCC) is promising in recent years, but still facing critical challenges. The first targeted therapy, sorafenib, prolonged the overall survival by months.
Junjie Xu, Lin Ji, Yeling Ruan, Zhe Wan, Zhongjie Lin, Shunjie Xia, Liye Tao, Junhao Zheng, Liuxin Cai, Yifan Wang, Xiao Liang, Xiujun Cai   +11 more
doaj   +1 more source

Correction to: The life expectancy of patients with metabolic syndrome after weight loss: study protocol for a randomized clinical trial (LIFEXPE-RT)

Trials, 2019
Following publication of the original article [1], the authors notified us of a typing error in spelling Dr. Yeleuov’s name. The original publication has been corrected.
Oral Ospanov, Galymzhan Yeleuov, Irina Kadyrova, Farida Bekmurzinova   +3 more
doaj   +1 more source

Inhibition of Cholesterol Esterification Enzyme Enhances the Potency of Human Chimeric Antigen Receptor T Cells against Pancreatic Carcinoma

Molecular Therapy: Oncolytics, 2020
This study aimed to assess the effectiveness of inhibiting cholesterol acyltransferase 1 (ACAT-1) in chimeric antigen receptor T (CAR-T) cells on potentiating the antitumor response against mesothelin (MSLN)-expressing pancreatic carcinoma (PC) cells. We
Lei Zhao, Yang Liu, Fuya Zhao, Ye Jin, Jing Feng, Rui Geng, Jiayu Sun, Liqing Kang, Lei Yu, Yunwei Wei   +9 more
doaj   +1 more source

Circ-RAPGEF5 promotes intrahepatic cholangiocarcinoma progression by stabilizing SAE1 to facilitate SUMOylation

Journal of Experimental & Clinical Cancer Research, 2023
Background Intrahepatic cholangiocarcinoma (ICC) is an aggressive malignancy with a poor prognosis. The underlying functions and mechanisms of circular RNA and SUMOylation in the development of ICC remain poorly understood.
Junhao Zheng, Yali Wang, Liye Tao, Jingwei Cai, Zefeng Shen, Yang Liu, Haoyu Pan, Shihao Li, Yeling Ruan, Tianyi Chen, Zhengtao Ye, Kainan Lin, Yin Sun, Junjie Xu, Xiao Liang   +14 more
doaj   +1 more source

Endoscopic versus laparoscopic treatment for choledocholithiasis: a prospective randomized controlled trial

Endoscopy International Open, 2016
Background and study aims: Overall, 5 % to 15 % of patients undergoing cholecystectomy for cholelithiasis have concomitant bile duct stones, and the incidence of choledocholithiasis increases with age.
Javier Ernesto Barreras González, Rafael Torres Peña, Julián Ruiz Torres, Miguel Ángel Martínez Alfonso, Raúl Brizuela Quintanilla, Maricela Morera Pérez   +5 more
doaj   +1 more source

Laparoscopic adrenalectomy

British Journal of Surgery, 2004
AbstractBackgroundLaparoscopic adrenalectomy (LA) has become the procedure of choice for small benign lesions. Compared with open adrenalectomy (OA), it appears to achieve superior results in terms of recovery, cosmesis and morbidity.MethodsA Medline literature search (PubMed database, 1990–2003) was undertaken to identify relevant English language ...
A, Assalia, M, Gagner
openaire   +2 more sources

Suprapubic single-incision laparoscopic right colectomy with complete mesocolic excision, lateral-to-medial approach and intracorporeal anastomoses

International Journal of Gastrointestinal Intervention, 2019
Background : Single-incision laparoscopic right colectomy (SILRC) has been reported in 2008, and since that time an increased number of reports appeared in literature. Currently, it remains popular between the centers with achieved experience.
Giovanni Dapri, Kelly Ann Bobb, Ernesto Jesús Barzola Navarro, Angel Arabadzhiev   +3 more
doaj   +1 more source

Short-Term Results of Sclerotherapy with 3% Polidocanol Foam for Symptomatic Second- and Third-Degree Hemorrhoidal Disease

Journal of Investigative Surgery, 2021
Background Hemorrhoidal disease (HD) is defined as the symptomatic enlargement and/or distal displacement of anal cushions and is one of the most common proctological diseases.
Pierluigi Lobascio, Rita Laforgia, Eugenio Novelli, Fabrizio Perrone, Maria Di Salvo, Angela Pezzolla, Mario Trompetto, Gaetano Gallo   +7 more
doaj   +1 more source

Laparoscopic adrenalectomy

Journal of Minimal Access Surgery, 2005
Laparoscopic adrenalectomy is currently recognized as the gold standard for the treatment of adrenal tumors. In order to assess the current status of laparoscopic adrenalectomy, we reviewed the literature focusing on the indications and contraindications, surgical techniques, complications and new methods.
Tsuru Nobuo, Suzuki Kazuo
openaire   +3 more sources

Liver Abscess and Pseudotumoral Gastric Lesion Caused by Chicken Bone Perforation: Laparoscopic Management

Case Reports in Surgery, 2012
The accidental ingestion of a foreign body into the gastrointestinal tract is not uncommon, but the vast majority of foreign bodies pass through the gastrointestinal tract uneventfully within a week.
Gabriele Ricci, Nello Campisi, Giovanni Capuano, Luigi De Vido, Luca Lazzaro, Giuliana Simonatto, Barbara Termini, Valeria Turriziani, Francesco Fidanza   +8 more
doaj   +1 more source