Results 121 to 130 of about 1,208,182 (388)

Targeting SPHK1 in macrophages remodels the tumor microenvironment and enhances anti‐PD‐1 immunotherapy efficacy in colorectal cancer liver metastasis

Cancer Communications, EarlyView.
Abstract Background Colorectal cancer liver metastasis (CRLM) is characterized by an immunosuppressive microenvironment and a blunted response to immunotherapy. Notably, tumor‐associated macrophages (TAMs) play a critical role in modulating immune responses and exhibit significant heterogeneity in CRLM.
Yizhi Zhan, Jinsong Xu, Zhanqiao Zhang, Yating Hu, Yongsheng Li, Junying Qian, Yunyan Ling, Dehua Wu, Haijun Deng, Guoxin Li, Zhiyong Shen, Yuan Fang   +11 more
wiley   +1 more source

Incisional abdominal hernia repair with concomitant abdominoplasty: Maintaining umbilical viability

JPRAS Open, 2018
Introduction: Abdominoplasty and abdominal hernia repair are often carried out in two-stage procedures, and those describing single-stage surgery require careful dissection to preserve often only partial blood supply to the umbilicus to maintain its ...
Robert Phan, Elan Kaplan, Jemma K. Porrett, Yik-Hong Ho, Warren M. Rozen   +4 more
doaj  

Comparison of Laparoscopic versus Open Approach for Repair of Lumbar Hernia: A Case Series Analysis at AIIMS Bhubaneswar

NMO Journal
Introduction: Lumbar hernia repair is a rare and challenging surgical procedure. Both laparoscopic and open techniques are employed, but a comparison of outcomes in terms of recurrence, postoperative pain, length of hospital stay and wound infection ...
Rahul Kumar, Ankit Rana, Shantanu Kumar Sahu, Manvar Ali, Monika Gureh, Manash Ranjan Sahoo   +5 more
doaj   +1 more source

Corrective treatment and anatomic considerations for laparoscopic cholecystectomy injuries [PDF]

, 1994
BACKGROUND: Complete reports of biliary and vascular injuries after laparoscopic cholecystectomy are rare. STUDY DESIGN: Fifteen patients with complex laparoscopic cholecystectomy injuries underwent corrective operations.
Dodson, SF, Iwatsuki, S, Madariaga, JR, Selby, R, Starzl, TE, Todo, S   +5 more
core  

Gastric perforation and pancreatitis manifesting after an inadvertent nissen fundoplication in a patient with superior mesenteric artery syndrome. [PDF]

, 2009
Superior mesenteric artery (SMA) syndrome is an uncommon but well-recognized clinical entity. It can lead to proximal small bowel obstruction and severe morbidity and mortality in lieu of late diagnosis and concomitant existing comorbidities. We report a
Estrada, JJ, Giuliani, S, Mason, RJ, Petrosyan, M, Rosen, H, Williams, M   +5 more
core   +3 more sources

Laparoscopic versus open pediatric inguinal hernia repair: state-of-the-art comparison and future perspectives from a meta-analysis

Surgical Endoscopy, 2019
BackgroundLaparoscopic inguinal hernia repair in children is increasingly performed as it allows contralateral inspection and potentially results in shorter operation time and less complications.
K. Dreuning, Sanne C Maat, J. Twisk, E. van Heurn, J. Derikx   +4 more
semanticscholar   +1 more source

The challenges faced in the design, conduct and analysis of surgical randomised trials [PDF]

, 2009
Randomised evaluations of surgical interventions are rare; some interventions have been widely adopted without rigorous evaluation. Unlike other medical areas, the randomised controlled trial (RCT) design has not become the default study design for the ...
Cook, Jonathan Alistair
core  

Conscious monitoring and control (reinvestment) in surgical performance under pressure. [PDF]

, 2012
Research on intraoperative stressors has focused on external factors without considering individual differences in the ability to cope with stress. One individual difference that is implicated in adverse effects of stress on performance is "reinvestment,"
A Prabhu, AI Thuraisingam, AP Tendulkar, B Bohm, BJ Chell, CM Liao, CM Wetzel, CY Wan, DJ Scott, EM Ritter, FF Zhu, FF Zhu, I Hassan, J Sexton, Jamie M. Poolton, JM Poolton, JM Poolton, JP Maxwell, JP Maxwell, JP Maxwell, JP Poolton, K Moorthy, Karen Ngo, Mark R. Wilson, MR Wilson, MW Eysenck, MW Eysenck, Neha Malhotra, NP Kinrade, NP Kinrade, PB Andreatta, R Berguer, Rich S. W. Masters, RS Holzman, RS Lazarus, RSW Masters, RSW Masters, RSW Masters, RSW Masters, RSW Masters, RSW Masters, RSW Masters, RSW Masters, RSW Masters, S Arora, S Arora, S Arora, S Arora, S Yule, SK Sarker, TM Marteau, V Datta, V Datta, WL Wong   +53 more
core   +2 more sources

Conversion therapy with sintilimab combined with chemotherapy and apatinib in stage IV gastric cancer

International Journal of Cancer, EarlyView.
What's New? In selected patients with stage IV gastric cancer, radical surgery after conversion therapy may increase survival benefit; however, there is currently no standard protocol for conversion therapy. This prospective, single‐arm, single‐center, phase 2 study evaluated the feasibility of adding immunotherapy to a conversion treatment regimen to ...
Yong Liu, Qiang Xue, Baogui Wang, Xuewei Ding, Rupeng Zhang, Xiaona Wang, Bin Ke, Xuejun Wang, Ning Liu, Jingyu Deng, Hongjie Zhan, Bin Li, Liangliang Wu, Mingzhi Cai, Li Zhang, Wenbai Huang, Peng Jin, Han Liang   +17 more
wiley   +1 more source

Laparoscopic Emergency Surgery for Perforated Peptic Ulcer: A Narrative Review [PDF]

Journal of Acute Care Surgery
Perforated peptic ulcer (PPU) is developed in 2%–10 % of peptic ulcer. The essential treatment is emergent surgical repair. Usually, the surgical repair with or without an omental patch is performed by laparotomy. The laparoscopic emergency surgery (LES)
Jung Min Bae
doaj   +1 more source