Results 211 to 220 of about 711,055 (261)

When Current Severity Overrides Reassuring Findings: TG18‐Guided Biliary Drainage in ERCP‐Confirmed Purulent Cholangitis

open access: yesClinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT A 42‐year‐old antibiotic‐naïve man with previous laparoscopic cholecystectomy and poorly controlled type 2 diabetes mellitus (HbA1c 9.7%) presented with Charcot's triad 7 days after a formally documented normal hepatobiliary evaluation (alanine aminotransferase [ALT] 22 U/L; total bilirubin 0.7 mg/dL [12 μmol/L]; common bile duct [CBD] ≤ 5 mm ...
Hatem Mousa Taha, Khaled Hatem Taha
wiley   +1 more source

Gastric Emptying in Obesity and Weight‐Loss Interventions: Physiology, Assessment, and Clinical Implications

open access: yesComprehensive Physiology, Volume 16, Issue 5, October 2026.
Obesity is associated with accelerated gastric emptying. Weight‐loss interventions each impose a distinct emptying signature: acceleration after sleeve gastrectomy and gastric bypass, delay after endoscopic sleeve gastroplasty, intragastric balloon, and GLP‐1 receptor agonists.
Maxime Amoyel   +4 more
wiley   +1 more source

Identification of a Functional CYP2C8 Variant Allele that Alters Splicing, Reduces Protein Expression, and Increases Drug Exposure

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 4, Page 966-978, October 2026.
This study investigated genetic determinants of the pharmacokinetics of the CYP2C8 index drugs repaglinide and gemfibrozil, and their interaction in healthy participants. Sequencing data from a study with montelukast revealed a novel functional CYP2C8 allele (rs2071426, CYP2C8*19), predicted to create an intronic splice donor site.
Anssi J. H. Mykkänen   +14 more
wiley   +1 more source

Preoperative and postoperative pathology concordance in endometrial intraepithelial neoplasia: A retrospective cohort study

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 175, Issue 1, Page 336-344, October 2026.
Abstract Objective To assess the concordance between pre‐ and postoperative pathology in patients with endometrial intraepithelial neoplasia (EIN) undergoing hysterectomy, and identify predictors of malignancy, including sampling method, progestin therapy, and surgical timing.
Jenny Dimakos   +6 more
wiley   +1 more source

Indocyanine green for intraoperative ureteral identification in gynecologic surgery: A preliminary systematic review of feasibility, safety, and surgical outcomes

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 175, Issue 1, Page 67-76, October 2026.
Abstract Background Intraoperative ureteral injury, although uncommon, can result in significant morbidity and medicolegal consequences, particularly during complex gynecologic procedures such as endometriosis excision and prolapse repair. Conventional ureteral identification techniques, including stents and methylene blue, have recognized limitations.
Victoria Zhang   +3 more
wiley   +1 more source

Transcervical Epiglottic Suspension for Severe Type III Laryngomalacia in Infants: Feasibility, Safety, and Effectiveness

open access: yesLaryngoscope Investigative Otolaryngology, Volume 11, Issue 5, October 2026.
ABSTRACT Objective To evaluate the feasibility, safety, and clinical outcomes of transcervical epiglottic suspension in respiratory support‐dependent infants with Type III laryngomalacia. Methods This retrospective case series at a single‐center tertiary children's hospital included consecutive infants with endoscopically confirmed Type III ...
Weiguang Yang   +6 more
wiley   +1 more source

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