Results 231 to 240 of about 195,541 (304)

Treatment landscape from first‐ to third‐line therapy and quality of life data of patients with pancreatic cancer from the prospective German PARAGON (Platform for Outcome, Quality of Life, and Translational Research on Pancreatic Cancer) registry (IKF‐PARAGON study)

open access: yesInternational Journal of Cancer, Volume 158, Issue 10, Page 2560-2570, 15 May 2026.
What's New? Pancreatic cancer often is diagnosed at advanced stages. As a result, treatment regimens frequently are aggressive, with substantial side effects that impact quality of life (QoL). This study examined the treatment landscape, from neoadjuvant therapy to palliative care, in the context of QoL among pancreatic cancer patients in Germany. Most
Thorsten O. Goetze   +19 more
wiley   +1 more source

Efficacy and Safety Assessment of 5‐Fluorouracil, Irinotecan and Oxaliplatin‐Loaded Implants in Mouse and Pig Models for Pancreatic Cancer Therapy

open access: yesAdvanced Materials, Volume 38, Issue 26, 8 May 2026.
A novel FIRINOX‐loaded implant demonstrates controlled drug release, and potent therapeutic efficacy in pancreatic ductal adenocarcinoma mouse models with safety confirmed in a large‐animal pre‐clinical model. This innovative drug delivery platform offers a promising new treatment approach for non‐resectable, treatment‐resistant pancreatic cancer ...
Samantha J. Wade   +19 more
wiley   +1 more source

Surgery in space: The ultimate frontier

open access: yes
Experimental Physiology, EarlyView.
Mohamad Bashir   +5 more
wiley   +1 more source

Postoperative Stress Accelerates Atherosclerosis Through Inflammatory Remodeling of the HDL Proteome and Impaired Reverse Cholesterol Transport

open access: yesAdvanced Science, Volume 13, Issue 26, 8 May 2026.
The study shows that noncardiac surgical inflammation rapidly disrupts HDL function and cholesterol efflux in mice and human patients. Impaired reverse cholesterol transport after surgery drives rapid lipid accumulation, NETosis, and apoptosis within atherosclerotic plaques.
Dominique M. Boucher   +15 more
wiley   +1 more source

When Silence Speaks: A Perforated Hepatic Cyst, Intact Omental Cyst, and Cholelithiasis

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT A 39‐year‐old man from an echinococcosis‐endemic region presented with acute left upper quadrant pain. Imaging revealed cholelithiasis, a hepatic and a large abdominal cystic masses, and significant free peritoneal fluid. Urgent laparotomy unexpectedly disclosed three concurrent pathologies: chronic calculous cholecystitis, a perforated ...
Mohadese Hematian   +5 more
wiley   +1 more source

Heterotopic pregnancy in a patient with severe hypothyroidism: a rare case report. [PDF]

open access: yesJ Surg Case Rep
Alkhateeb D   +5 more
europepmc   +1 more source

Large Symptomatic Splenic Pseudocyst: Case Report of a Rare Entity

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Large symptomatic splenic pseudocysts, though rare, should be considered in patients with persistent left upper abdominal pain as we report in our case. Imaging enables diagnosis, and laparoscopic spleen‐preserving cyst decompression and deroofing provide a safe, effective treatment, relieving symptoms while maintaining splenic function and ...
Tasnuva Habib Neha   +3 more
wiley   +1 more source

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