Results 121 to 130 of about 157,237 (248)

Adaptive Machine Learning Framework for Optimizing the Affinity Purification of Adeno‐Associated Viral Vectors

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Adeno‐associated viral (AAV) vectors for gene therapy are becoming integral to modern medicine, providing therapeutic options for diseases once deemed incurable. Currently, viral vector purification is a critical bottleneck in the gene therapy industry, impacting product efficacy and safety as well as accessibility and cost to patients ...
Kelvin P. Idanwekhai, Shriarjun Shastry, Morgan R. Hurst, Arianna Minzoni, Eduardo Barbieri, Luke Remmler, Eugene N. Muratov, Michael A. Daniele, Stefano Menegatti, Alexander Tropsha   +9 more
wiley   +1 more source

Influence of Inlet Boundary Conditions on the Prediction of Flow Field and Hemolysis in Blood Pumps Using Large-Eddy Simulation. [PDF]

Bioengineering (Basel), 2023
Xiang WJ, Huo JD, Wu WT, Wu P.
europepmc   +1 more source

Large-eddy simulation of a turbulent mixing layer [PDF]

The three dimensional, time dependent (incompressible) vorticity equations were used to simulate numerically the decay of isotropic box turbulence and time developing mixing layers.
Ferziger, J. H., Mansour, N. N., Reynolds, W. C.   +2 more
core   +1 more source

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source

Large-Eddy Simulation on the Aerodynamic and Thermal Characteristics in a Micropipe of the Hypersonic Engine Precooler. [PDF]

Micromachines (Basel), 2022
Zhang J, Zou Z, Wang Y.
europepmc   +1 more source

Shaping research in marine functional connectivity for integrated and effective marine science and management

Biological Reviews, EarlyView.
ABSTRACT Effective knowledge of ecological connectivity at sea and at the land–sea interface is key to supporting global policy goals to conserve and restore ocean biodiversity and function. However, a persistent lack of commonality in terminology and understanding around the concept of connectivity in marine ecological studies hampers its integration ...
Audrey M. Darnaude, Susanne E. Tanner, Andreu Blanco, Anna M. Sturrock, Yael Teff Seker, Angel Pérez‐Ruzafa, Jonne Kotta, Tamar Guy‐Haim, Francisco R. Barboza, Manuel Hidalgo, Katell Guizien, Jerneja Penca, Lucía López‐López, Maria Beger, Federica Costantini, Sophie Arnaud‐Haond, Cynthia Riginos, Kris Hostens, Gil Rilov, Stelios Katsanevakis, Ewan Hunter   +20 more
wiley   +1 more source

Numerical Modeling of Transient Flow Characteristics on the Top Surface of a Steel Slab Continuous Casting Strand Using a Large Eddy Simulation Combined with Volume of Fluid Model. [PDF]

Materials (Basel), 2023
Tian Y, Zhou H, Wang G, Xu L, Qiu S, Zhu R.   +5 more
europepmc   +1 more source

Development of a Mechanically Regenerating Desublimator for Freeze‐Drying Systems in the Food Industry

Chemie Ingenieur Technik, EarlyView.
Thermal defrosting limits desublimator efficiency in freeze‐drying. This review and case study compares thermal versus mechanical regeneration, links frost properties and external heat transfer to energy demand, and summarizes pilot‐scale scraping results enabling single‐unit, continuous lyophilization.
Moritz Krummenacher, Mirko Kleingries, Edgar Zimmer, Roman Blättler   +3 more
wiley   +1 more source

CFD Simulation of Particle-Laden Flow in a 3D Differentially Heated Cavity Using Coarse Large Eddy Simulation. [PDF]

Flow Turbul Combust, 2022
Sayed MA, Dehbi A, Hadžiabić M, Ničeno B, Mikityuk K.   +4 more
europepmc   +1 more source

Effect of different flue gas recirculation rates on low‐NOx combustion characteristics: A numerical simulation based on the combustion process of a gas boiler

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract NOx emissions from gas boilers severely impact the environment, and flue gas recirculation (FGR) technology can effectively reduce such emissions, yet the effects of different FGR rates on combustion performance and NOx formation remain unclear. This study thus used numerical simulation (via ANSYS Fluent, adopting the realizable k‐ε turbulence
Chao Min, Shuhao Xu, Yitao Yang, Peng Wang   +3 more
wiley   +1 more source