Proinflammatory protein signatures in cryptogenic and large artery atherosclerosis stroke. [PDF]
The cause of ischemic stroke remains unknown, cryptogenic, in 25% of young and middle‐aged patients. We hypothesized that if atherosclerosis is prominent in cryptogenic stroke, it would have a similar proinflammatory protein signature as large artery ...
Holmegaard L +7 more
europepmc +10 more sources
Update on Biomarkers Associated with Large-Artery Atherosclerosis Stroke. [PDF]
Intracranial and extracranial large-artery atherosclerosis (LAA) are a main cause of ischemic stroke. Biomarkers may aid in the diagnosis of LAA and help to stratify patients’ risk of stroke.
Rosário M, Fonseca AC.
europepmc +5 more sources
Machine learning approaches for biomarker discovery to predict large-artery atherosclerosis. [PDF]
Large-artery atherosclerosis (LAA) is a leading cause of cerebrovascular disease. However, LAA diagnosis is costly and needs professional identification. Many metabolites have been identified as biomarkers of specific traits.
Sun TH, Wang CC, Wu YL, Hsu KC, Lee TH.
europepmc +5 more sources
Fibrinogen-to-Albumin Ratio and Clinical Outcomes in Patients With Large Artery Atherosclerosis Stroke. [PDF]
Background A high fibrinogen‐to‐albumin ratio (FAR), a novel inflammatory marker, is considered to be a prognostic marker in vascular diseases. However, the association of FAR with large artery atherosclerosis (LAA) stroke is still unknown.
Wang Y, Bai L, Li X, Yi F, Hou H.
europepmc +5 more sources
Ischemic stroke caused by large-artery atherosclerosis: a red flag for subclinical coronary artery disease. [PDF]
Background The coronary calcium score (CAC) measured on chest computerized tomography is a risk marker of cardiac events and mortality. We compared CAC scores in two multiethnic groups without symptomatic coronary artery disease: subjects in the chronic ...
de Araújo ALV +13 more
europepmc +2 more sources
High ApoB/ApoA-I Ratio Predicts Post-Stroke Cognitive Impairment in Acute Ischemic Stroke Patients with Large Artery Atherosclerosis. [PDF]
Background: We aimed to investigate the association between the ApoB/ApoA-I ratio and post-stroke cognitive impairment (PSCI) in patients with acute stroke of large artery atherosclerosis etiology.
Lee M +9 more
europepmc +2 more sources
Intra-arterial tenecteplase is safe and may improve the first-pass recanalization for acute ischemic stroke with large-artery atherosclerosis: the BRETIS-TNK trial. [PDF]
Background and purpose The first-pass recanalization of endovascular treatment (EVT) is closely correlated with clinical outcome of patients with large vessel occlusion (LVO) stroke. The aim of the study was to explore whether intra-arterial tenecteplase
Zhao ZA +10 more
europepmc +2 more sources
Inflammatory Burden Index and One-Year Clinical Outcomes in Large Artery Atherosclerosis Ischemic Stroke: A Multicenter Prospective Study. [PDF]
The inflammatory burden index (IBI) is a novel composite biomarker designed to assess systemic inflammation, but its prognostic value in large‐artery atherosclerosis (LAA) ischemic stroke remains unestablished.
Mo J +7 more
europepmc +2 more sources
Endovascular treatment for acute basilar artery occlusion due to different stroke etiologies of large artery atherosclerosis and cardioembolism. [PDF]
Introduction: Stroke etiology may affect the prognosis of acute basilar artery occlusion (BAO). This study aimed to estimate the efficacy and safety of endovascular treatment (EVT) in BAO strokes due to the underlying stroke etiologies of large artery ...
Liu H +13 more
europepmc +2 more sources
Lipoprotein(a) and large artery atherosclerosis: results from the BIOSIGNAL study. [PDF]
Abstract Background Lipoprotein(a) (Lp(a)) is a causal risk-factor for atherosclerotic cardiovascular disease including acute ischemic stroke (AIS). The underlying pathomechanisms mediating this risk are less well understood, especially in AIS caused by large artery atherosclerosis (LAA).
Gross F +11 more
europepmc +4 more sources

