Results 91 to 100 of about 9,099,533 (275)

Low adiponectin levels are an independent predictor of mixed and non-calcified coronary atherosclerotic plaques. [PDF]

, 2009
Atherosclerosis is the primary cause of coronary artery disease (CAD). There is increasing recognition that lesion composition rather than size determines the acute complications of atherosclerotic disease.
Lebherz Corinna, Renee Stark, Christoph Becker, Stark, R.G., Stark, Renee, Tittus, Janine, Lehrke Michael, Lebherz, C., Greif, Martin, Greif Martin, Broedl Uli C., Reiser, M., Stark Renee, Reiser, Maximilian, Ziegler, Franz von, Alexander W Leber, Göke, B., Parhofer, K.G., Lebherz, Corinna, Alexander Becker, Leber, A.W., Leber, Alexander W., Michael Lehrke, Corinna Lebherz, Lehrke, Michael, Greif, M., von Ziegler Franz, Parhofer Klaus G., von Ziegler, A., Göke, Burkhard, Parhofer, Klaus G., Janine Tittus, Becker, C., Becker Alexander, Broedl, U.C., Reiser Maximilian, Broedl, Uli C., Martin Greif, Klaus G Parhofer, Tittus, J., Tittus Janine, Burkhard Göke, Göke Burkhard, Becker, F., Becker, Alexander, Maximilian Reiser, Uli C Broedl, Becker, Christoph, Becker Christoph, Leber Alexander W., Franz von Ziegler, Lehrke, M.   +51 more
core   +2 more sources

Targeting a Calcium‐Associated Mitochondrial Vulnerability in TET2‐Deficient Myeloid Cells

Advanced Science, EarlyView.
Reduced TET2 function creates a calcium‐associated mitochondrial vulnerability in macrophages that is preferentially exploited by Lanatoside C. The resulting stress promotes apoptosis of TET2‐deficient macrophages, reduces inflammatory and fibrotic injury in human cardiac organoids, and highlights a genotype‐associated myeloid liability that may be ...
Yue Wang, Minh Duc Pham, Despina Stefanoska, Ting Yuan, Arka Provo Das, Chaonan Zhu, Meiqian Wu, Thanh Thuy Duong, Jaskiran Kaur, Yu Hao, Johannes Krefting, Marius Schwab, Jonathan Ward, Maria Duda, Wesley Abplanalp, Moritz von Scheidt, Andreas M. Zeiher, Stefanie Dimmeler, Jaya Krishnan   +18 more
wiley   +1 more source

Implantable Systems for Cardiovascular Treatment and Monitoring: Comparative Insights From Intracardiovascular and Extracardiovascular Technologies

Advanced Intelligent Systems, EarlyView.
A unifying device–cardiovascular interface framework is presented to classify implantable cardiovascular technologies as intracardiovascular blood‐contacting systems or extracardiovascular tissue‐only and blood‐handling architectures. Cross‐class comparison across shared semiquantitative criteria, including blood‐contact burden, biomimicry ...
Bergo Nicolò, Semproni Federica, Maselli Martina, Colli Andrea, Cianchetti Matteo, Ciuti Gastone, Stefanini Cesare, Menciassi Arianna   +7 more
wiley   +1 more source

Study of the Inflammatory Mechanisms in Hyperhomocysteinemia on Large-Artery Atherosclerosis Based on Hypersensitive C-Reactive Protein-A Study from Southern China.

Journal of Stroke & Cerebrovascular Diseases, 2019
OBJECTIVE To study the inflammatory mechanism of hyperhomocysteinemia on large-artery atherosclerosis based on hypersensitive C-reactive protein in patients. METHODS In all, 153 inpatients and 1357 physical examinees were selected.
Li-Ming Cao, Yi Guo, Zhishan Zhu
semanticscholar   +1 more source

Animal stroke models and outcome evaluation: A review

Animal Models and Experimental Medicine, EarlyView.
Rodents are the preeminent stroke model species. Large animal models exist too, but are poorly standardized. Ischemic and hemorrhagic experimental models are available, with the intraluminal filament model being predominant. Outcomes are evaluated via quantifying subjects' sensorimotor impairment, cognitive memory faculties, degree of cellular ...
Solsa Cariba, Helen M. Atkinson, Anthony K. C. Chan   +2 more
wiley   +1 more source

Silk Fibroin for Cardiovascular Medical Devices: Review of Material Properties, Applications, and Clinical Potential

Advanced NanoBiomed Research, EarlyView.
Silk fibroin is an attractive natural biomaterial that can be engineered into diverse cardiovascular constructs, including vascular grafts, cardiac patches, heart valves, and stent coatings. Its tunable biological and mechanical properties have driven substantial preclinical progress; however, widespread clinical translation in cardiovascular ...
Mahsa Haghighattalab, Matt Govendir, Kristina Andelovic, Zachary Och, Fatemeh Karimi, Munira Xaymardan, Tomasz Jungst, Jelena Rnjak‐Kovacina, Nona Farbehi   +8 more
wiley   +1 more source

Statin Pretreatment and Microembolic Signals in Large Artery Atherosclerosis: A Systematic Review and Meta-Analysis

Stroke, 2018
Background and Purpose— Scarce data indicate that statin pretreatment (SP) in patients with acute cerebral ischemia because of large artery atherosclerosis may be related to lower risk of recurrent stroke because of a decreased incidence of microembolic ...
A. Safouris, A. Katsanos, A. Kerasnoudis, C. Krogias, J. Kinsella, R. Sztajzel, V. Lambadiari, S. Deftereos, O. Kargiotis, V. K. Sharma, A. Demchuk, M. Saqqur, D. J. H. McCabe, G. Tsivgoulis   +13 more
semanticscholar   +1 more source

Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source

Noninvasive Imaging of Carotid Arterial Strain Using Displacement-Encoded MRI [PDF]

, 2009
Stroke is the leading cause of disability in the United States and the third leading cause of death. These “brain attacks” occur when atherosclerosis, the progressive process of thickening and hardening of arterial walls, develops in the carotid ...
Lin, Alexander Pei-Den Peter
core   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source