Results 161 to 170 of about 9,099,533 (275)

Current status and future perspectives of platelet function‐guided precision antiplatelet therapy for patients with cerebral infarction

Neuroprotection, EarlyView.
Antiplatelet agents target the cyclooxygenase‐1 (COX‐1)/thromboxane A2 (TXA2) and adenosine diphosphate (ADP)‐P2Y12 (cytochrome P450 2C19 [CYP2C19]‐metabolized) platelet activation pathways, resulting in either drug resistance or over‐inhibition. The individualized therapeutic window balances ischemic risk (triggered by high on‐treatment platelet ...
Guoliang Zhu, Xiaoling Chen, Xinyi Huang, Quandan Tan, Qing Cao, Yali Yang, Yapeng Lin, Jie Yang   +7 more
wiley   +1 more source

Correlation between inflammatory burden index and hemorrhage expansion among large-artery atherosclerosis acute ischemic stroke with hemorrhagic transformation. [PDF]

BMC Neurol
Yang Y, Han Y, Shen S, Wan M, Wu M, Zhang Y.   +5 more
europepmc   +1 more source

Burden of ischemic stroke in China from 1990 to 2050: A systematic review and analysis of Global Burden of Disease Study 2021

Neuroprotection, EarlyView.
Based on GBD 2021, the study analyzed the temporal trends of ischemic stroke (IS) burden in China from 1990 to 2021 and forecasted incidence and mortality through 2050. The absolute burden of IS in China will continue to rise by 2050, driven mainly by population aging, with faster age‐standardized incidence rate growth in females than males.
Yijun Zhang, Jinqiao Zhu, Xue Xia, Meng Gao, Yunyi Hao, Anxin Wang   +5 more
wiley   +1 more source

Thrombi from stroke due to cardioembolic etiology have higher CD11b-positive cells compared to large artery atherosclerosis. [PDF]

J Thromb Thrombolysis
Finger C, Emara G, Chiu GS, Li K, Sheth S, Tan C, Parekh M, Inam ME, Dongarwar D, Manwani B.   +9 more
europepmc   +1 more source

Clinical interpretation of cardiac troponin in athletes: From endurance exercise to exertional injury

PM&R, EarlyView.
Abstract Exertional heat illness (EHI) and exertional rhabdomyolysis (ER) are increasingly recognized causes of morbidity in competitive and tactical athletes. Cardiac troponin (cTn) elevation, traditionally viewed as a marker of myocardial necrosis, may also be seen in these settings and can create significant diagnostic and prognostic uncertainty ...
John‐Henry L. Dean, Jeffrey C. Leggit, M. Alaric Franzos   +2 more
wiley   +1 more source

Timely Initiation of Argatroban Improves Prognosis in Patients With Acute Ischemic Stroke Attributed to Large Artery Atherosclerosis: A Cohort Study. [PDF]

Brain Behav
Liu Q, Wu X, Huang D, Wang Y, Wu H, Zhu X.   +5 more
europepmc   +1 more source

Potential of Ginkgo biloba Extract to Intervene in Chronic Inflammation‐Related Diseases

Phytotherapy Research, EarlyView.
Chronic inflammation is a pathological mechanism underpinning many diseases. Ginkgo biloba extract (GBE) is well known for its anti‐inflammatory property. GBE and its active constituents have been shown to attenuate pro‐inflammatory cytokine production, suppress nuclear factor kappa B activation, restore redox homeostasis, and modulate disease‐relevant
Yipeng Lin, Inho Cho, Xue Zhu, Ke Wang, Ling Zhu, Wenchang Wong, Michael Murray, Fanfan Zhou   +7 more
wiley   +1 more source

Microfluidics Lab‐on‐a‐Chip Approaches to Decipher Atherosclerosis Pathogenesis

Small, EarlyView.
Figure created with BioRender.com. This review highlights how microfluidic lab‐on‐a‐chip models recreate key features of atherosclerosis in controlled, human‐relevant environments. It summarizes advances in modeling endothelial dysfunction, immune cell recruitment, foam cell formation, vascular remodeling, stenosis, and plaque rupture.
Fahima Akther, Hang Thu Ta
wiley   +1 more source

Sex-Specific Association between HO-1 (GT)n Promoter Polymorphism and Large-Artery Atherosclerosis Stroke. [PDF]

J Atheroscler Thromb
Li J, Chen J, Wen J, Cheng K, Fu X, Li S, Shi Z.   +6 more
europepmc   +1 more source

The Relationship Between Blood Lipids, Coagulation Indexes, Blood Homocysteine and Sudden Deafness: A Retrospective Study and Mendelian Randomization Analysis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Certain blood components, including blood lipids, coagulation parameters, and homocysteine, have been suggested to correlate with the incidence and prognosis of sudden sensorineural hearing loss (SSNHL). However, the nature of these associations remains controversial.
Feng‐Xin Yang, Yu‐Wan Song, Yan Wang, Kun Zhao, Hu‐Hui‐Fen He, Jing‐Jing Qiu, Da‐Wei Liu, Bo Li, Yan Sun   +8 more
wiley   +1 more source