Results 231 to 240 of about 3,266,852 (276)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Case Report: One case of pregnancy complicated by large cell neuroendocrine carcinoma of the cervix with syndrome of inappropriate secretion of antidiuretic hormone. [PDF]

Front Oncol
Dong C, Zhu B, Miao G, Zheng Z.
europepmc   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Prognostic models for large cell neuroendocrine lung carcinoma: a machine learning and regression approach. [PDF]

Transl Lung Cancer Res
Gong X, Pan M, Lin Y, Ye X, Qian J, Liao G, Du J, Zheng B, Chen C, Yang Z.   +9 more
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Molecular Insights into the Diagnosis of Anaplastic Large Cell Lymphoma: Beyond Morphology and Immunophenotype. [PDF]

Int J Mol Sci
Frutos Díaz-Alejo J, Prieto-Potín I, Manso R, Rodríguez M, Rebollo-González M, Díaz de la Pinta FJ, Morales-Gallego M, Rodríguez-Pinilla SM, Onaindia A.   +8 more
europepmc   +1 more source

Diagnostic challenges and therapeutic strategies for large-cell neuroendocrine carcinoma of extrahepatic bile ducts: A rare case report. [PDF]

Medicine (Baltimore)
Zhang B, Qin Y, Zhang W, Gao Y, Ai X.
europepmc   +1 more source

BH3 mimetic drugs overcome the microenvironment-induced resistance to crizotinib in ALK+ anaplastic large cell lymphoma. [PDF]

Blood Adv
Pignataro C, Zoppoli P, Cappelli LV, Yoffe L, Moretti M, Izzo M, Mallia S, Kayembe C, Taylor A, Petrillo G, Affinito A, Quintavalle C, De Luca G, Mascolo M, Verde S, Fraticelli A, Ciarrocchi A, Salerno P, De Smaele E, Campese AF, Fragliasso V, Foà R, Merla G, Inghirami G, Condorelli G, Fiore D.   +25 more
europepmc   +1 more source

Corrigendum: Impact of CD3 expression on outcome in pediatric anaplastic large cell lymphoma. [PDF]

Front Oncol
Salah A, Hafez H, Semary S, Khorshed EN, Soliman S, Zaky I, Shahin SM, Lehmann L, ElHaddad A.   +8 more
europepmc   +1 more source

High-Throughput Molecular Characterization of the Microbiome in Breast Implant-Associated Anaplastic Large Cell Lymphoma and Peri-Implant Benign Seromas. [PDF]

Cancers (Basel)
Rogges E, Bertolazzi G, Vacca D, Borro M, Lopez G, Simmaco M, Scattone A, Firmani G, Sorotos M, Santanelli di Pompeo F, Noccioli N, Savino E, Vecchione A, Di Napoli A.   +13 more
europepmc   +1 more source