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The American Journal of Dermatopathology, 1992
Large-cell acanthoma is an epidermal neoplasm that is clinically, histologically, and biologically distinctive. Clinically, it differs from solar lentigo by being frequently skin-colored or hypopigmented. Histologically, it is defined by a population of uniformly large keratinocytes; it differs from solar lentigo by the absence of elongated ...
Rabinowitz AD, INGHIRAMI, Giorgio
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Large-cell acanthoma is an epidermal neoplasm that is clinically, histologically, and biologically distinctive. Clinically, it differs from solar lentigo by being frequently skin-colored or hypopigmented. Histologically, it is defined by a population of uniformly large keratinocytes; it differs from solar lentigo by the absence of elongated ...
Rabinowitz AD, INGHIRAMI, Giorgio
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International Journal of Dermatology, 2003
The large cell acanthoma presents as a slightly scaly tan macule on photodamaged skin. Clinically, it may be difficult to differentiate from a lentigo senilis, pigmented actinic keratosis, or a flat and pigmented seborrheic keratosis.We have studied 19 cases of large cell acanthoma.
Darius R, Mehregan +2 more
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The large cell acanthoma presents as a slightly scaly tan macule on photodamaged skin. Clinically, it may be difficult to differentiate from a lentigo senilis, pigmented actinic keratosis, or a flat and pigmented seborrheic keratosis.We have studied 19 cases of large cell acanthoma.
Darius R, Mehregan +2 more
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Intravascular large cell lymphoma
International Journal of Dermatology, 2007A 19‐year‐old female presented at our hospital with a 1‐year history of a 5‐cm indurated nontender lesion on the left shoulder. Two months later, a similar lesion appeared in the left mammary region, accompanied by necrosis and fever.At admission to our department, she presented disseminated lesions in the left submandibular region, the sternal area ...
Magdalena, Reyes-Castro +1 more
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Anaplastic large cell lymphoma
Head & Neck, 1991AbstractAnaplastic large cell lymphoma (ALCL) or Ki‐1 lymphoma is a recently described and distinctive non‐Hodgkin's lymphoma. Cervicofacial adenopathy caused by ALCL may mimic involvement by metastatic carcinoma or other malignancies common to the head and neck.
R D, Foss +4 more
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Angiotropic Large Cell Lymphoma
Southern Medical Journal, 1995Lymphomas are malignant neoplasms of cells native to lymphoid tissue that can arise anywhere in the body. Angiotropic large cell lymphoma (ALCL) is characterized by a proliferation of neoplastic mononuclear cells within the lumina of small blood vessels.
K A, Collins, G J, Davis
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Anaplastic large-cell lymphoma
Seminars in Diagnostic Pathology, 2011The concept of anaplastic large-cell lymphoma (ALCL) has changed over the years because of a stream of new information and novel understanding regarding the cell of origin, biology, genetics, and clinical features of these neoplasms. This new information has led to the current classification proposed by the expert reviewers of the World Health ...
INGHIRAMI, Giorgio +33 more
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Intravitreal Large-Cell Lymphoma
Mayo Clinic Proceedings, 1993Large-cell (non-Hodgkin's) lymphoma may occur in the eye as a cellular infiltrate in the vitreous, uveal tract (choroid), retina, or optic nerve. Lymphomatous involvement may be limited to the eye but also is frequently associated with lesions of the central nervous system.
H, Buettner, J P, Bolling
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Anaplastic Large Cell Neuroblastoma
Pediatric and Developmental Pathology, 2009Anaplastic large cell neuroblastomas (ALCNB) are a subset of undifferentiated neuroblastomas with marked pleomorphic and anaplastic features that render them diagnostically challenging. We reviewed the records of all patients diagnosed with ALCNB at Children's Healthcare of Atlanta (Egleston Children's Hospital) for their clinical, biologic, and ...
Carlos R, Abramowsky +3 more
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Large cell/neuroendocrine carcinoma
Lung Cancer, 2010Large cell neuroendocrine tumors of the lung represent a recently reclassified subtype of lung cancer with features of both small cell and non-small cell lung cancer. We review diagnostic difficulties, typical presentations, and the natural history of this tumor.
Russell, Gollard +3 more
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Anaplastic Large Cell Lymphoma
2014Anaplastic large cell lymphoma (ALCL) is a rare lymphoid malignancy that is characterized by the expression of CD30 cell surface receptor and by a chromosomal translocation that results in aberrant constitutive activation of the anaplastic large cell lymphoma kinase (ALK).
Younes A. +3 more
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