Results 51 to 60 of about 3,266,852 (276)

Large-scale transcriptomics analysis reveals a novel stress biomarker in CHO cells producing difficult to express mAbs

Scientific Reports
Monoclonal antibodies (mAbs) are considered one of the most game-changing products of the biopharmaceutical industry. The introduction of several diverse and complex formats consisting of several polypeptide chains and engineered with multiple antigen ...
Styliani Papadaki, Stella Tournaviti, Nicole Borth, Tobias Großkopf, Oliver Popp, Shan-Hua Chung, Tom Quaiser   +6 more
doaj   +1 more source

Renormalization group approach to an Abelian sandpile model on planar lattices

, 2002
One important step in the renormalization group (RG) approach to a lattice sandpile model is the exact enumeration of all possible toppling processes of sandpile dynamics inside a cell for RG transformations. Here we propose a computer algorithm to carry
A. Corral, A. Sornette, A. Vespignani, A. Vespignani, B. Drossel, B.D. Malamud, C. Tebaldi, C.-K. Hu, C.-K. Hu, C.-K. Hu, C.-K. Hu, C.-K. Hu, C.-K. Hu, C.-K. Hu, C.-K. Hu, C.-Y. Lin, Chai-Yu Lin, Chin-Kun Hu, D. Dhar, D. Dhar, D. Dhar, D.V. Ktiarev, E.V. Ivashkevich, E.V. Ivashkevich, E.V. Ivashkevich, J. Hasty, K. Chen, K. Christensen, L. Pietronero, P. Bak, P. Bak, P. Bak, R.V. Sole, S. Lübeck, S.N. Majumdar, S.S. Manna, S.S. Manna, S.S. Manna, S.S. Manna, S.S. Manna, S.S. Manna, V. Frette, V.B. Priezzhev, V.B. Priezzhev, V.B. Priezzhev, Vl.V. Papoyan, Y. Moreno   +46 more
core   +1 more source

Trop2 and its overexpression in cancers: regulation and clinical/therapeutic implications. [PDF]

, 2014
Trop2 is a transmembrane glycoprotein encoded by the Tacstd2 gene. It is an intracellular calcium signal transducer that is differentially expressed in many cancers. It signals cells for self-renewal, proliferation, invasion, and survival.
Bonavida, Benjamin, Shvartsur, Anna
core   +2 more sources

Stereotactic Body Radiation Therapy for Pediatric, Adolescent, and Young Adult Patients With Osteosarcoma: Local Control Outcomes With Dosimetric Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Osteosarcoma is a radioresistant tumor that may benefit from stereotactic body radiation therapy (SBRT) for locoregional control in metastatic/recurrent disease. We report institutional practice patterns, outcomes, toxicity, and failures in osteosarcoma patients treated with SBRT.
Jenna Kocsis, Shauna R. Campbell, Jonathan Jang, Eashwar Somasundaram, Chandana A. Reddy, Jacob G. Scott, Lilyana Angelov, Peter M. Anderson, Matteo Trucco, Zachary Burke, Lukas Nystrom, Nathan Mesko, Anthony Magnelli, Erin S. Murphy   +13 more
wiley   +1 more source

Molluscum contagiosum infection with features of primary cutaneous anaplastic large cell lymphoma [PDF]

, 2019
CD30+ T cell pseudolymphomas (CD30+ PSL) are a group of benign inflammatory cutaneous disorders that can develop in settings of viral infections or drug reactions.
Lee, Jason B, Nikbakht, Neda, Ringe, John, Shalabi, Doaa   +3 more
core   +1 more source

Primary mediastinal lymphoma: diagnosis and treatment options. [PDF]

, 2014
Primary mediastinal large B-cell lymphoma (PMBCL) is a unique B-cell lymphoma variant that arises from a putative thymic medulla B cell. It constitutes 2-4% of non-Hodgkin lymphomas and occurs most frequently in young females. PMBCL is characterized by a
DI ROCCO, Alice, Foa, Roberto, Martelli, Maurizio, Perrone, Salvatore, Russo, E   +4 more
core   +1 more source

Cerebrospinal Fluid Liquid Biopsy Enables Targeted Therapy Without Tissue Diagnosis in Pediatric Low‐Grade Gliomas With BRAF V600E Mutation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We present two pediatric cases of pediatric low‐grade gliomas (PLGG) with BRAF V600E mutations diagnosed and monitored using cerebrospinal fluid (CSF) liquid biopsy analyzed via digital droplet PCR (ddPCR), without tissue biopsy. Both patients were treated with dabrafenib and trametinib and monitored through clinical assessments, magnetic ...
Hannah Sultan, Damien Faury, Alexander G. Weil, Harrison J. Westwick, Nada Jabado, Sébastien Perreault   +5 more
wiley   +1 more source

Reversibility of lymphomas and lymphoproliferative lesions developing under cyclosporin-steroid therapy [PDF]

, 1984
Post-transplant lymphomas or other lymphoproliferative lesions, which were usually associated with Epstein-Barr virus infections, developed in 8, 4, 3, and 2 recipients, respectively, of cadaveric kidney, liver, heart, and heart-lung homografts ...
Atchison, RW, Bahnson, HT, Griffith, BP, Hakala, TR, Hardesty, RL, Ho, M, Iwatsuki, S, Jaffe, R, Nalesnik, MA, Porter, KA, Rosenthal, JT, Shaw, BW, Starzl, TE   +12 more
core   +1 more source

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed, Raquel Revuelta Iniesta, Mary Fewtrell, Julie Lanigan, Breeana Gardiner, Graeme O'Connor   +5 more
wiley   +1 more source

Primary anaplastic large T-cell lymphoma of the psoas muscle

Polish Journal of Pathology, 2021
Lymphomas presenting and mimicking soft-tissue masses are important to recognize, to avoid unnecessary treatment delays or extensive surgery. We describe a case of primary anaplastic large cell lymphoma (ALCL) arising from a deep skeletal muscle in a ...
Irene Pecorella, Angela Ferrari, Andrea Tornese, Quirino Lai, Gianluca Mennini, Massimo Rossi   +5 more
doaj   +1 more source