Results 111 to 120 of about 20,576,837 (316)
Nature CommunicationsPodocyte injury is central to diabetic kidney disease (DKD) pathogenesis, however, the mechanisms underlying podocyte loss remain unclear. Emerging evidence underscores the involvement of fibroblast growth factors (FGFs) in renal pathophysiology. Here we
Jie Zhou +19 more
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New Second-Order Finite Difference Scheme for the Problem of Contaminant in Groundwater Flow
Journal of Applied Mathematics, 2012 We develop a new efficient second-order finite difference scheme for two-dimensional problem of contaminant in groundwater flow. Theoretical analysis shows that the scheme is second-order convergence in the L2 norm and is unconditionally stable ...
Quanyong Zhu +3 more
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Cold Flows and Large Scale Tides [PDF]
, 1998 Several studies have indicated that the local cosmic velocity field is rather cold, in particular in the regions outside the massive, virialized clusters of galaxies. If our local cosmic environment is taken to be a representative volume of the Universe,
Hoffman, Yehuda, van de Weygaert, Rien
core +4 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
DC grids for integration of large scale wind power [PDF]
, 2011 It is widely recognized that the future wind power development in the Nordic region will be to a large extent be offshore. The most promising technology for that is the voltage source converter (VSC) HVDC. A review of the most important options and state-
Carlsson, Ola +8 more
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Investigating BSM Models with Large Scale Separation
, 2017 Mass-split systems based on a conformal infrared fixed point provide a low-energy effective description of beyond the standard model systems with large scale separation.
Hasenfratz, Anna +2 more
core +2 more sources
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
AntibioticsInfections caused by multidrug-resistant pathogens have emerged as a serious threat to public health. To develop new antibacterial agents to combat such drug-resistant bacteria, a class of novel amphiphilic xanthoangelol-derived compounds were designed ...
Siyu Yang +6 more
doaj +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Anti-inflammatory effects of para-quinone methide derivatives on ulcerative colitis
Frontiers in PharmacologyA series of para-quinone methide derivatives were evaluated their anti-inflammatory activity. Through the screening of the lipopolysaccharide (LPS)-induced inflammatory cell model in Raw264.7 cells, it was found that the inhibitory activity of meta ...
Yue Qiu +8 more
doaj +1 more source