Results 121 to 130 of about 20,576,837 (316)
LSDA: Large Scale Detection Through Adaptation [PDF]
, 2014 A major challenge in scaling object detection is the difficulty of obtaining labeled images for large numbers of categories. Recently, deep convolutional neural networks (CNNs) have emerged as clear winners on object classification benchmarks, in part ...
Darrell, Trevor +7 more
core
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Low-shot learning with large-scale diffusion
, 2018 This paper considers the problem of inferring image labels from images when only a few annotated examples are available at training time. This setup is often referred to as low-shot learning, where a standard approach is to re-train the last few layers ...
Douze, Matthijs +3 more
core +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
MicrobiomeBackground Alternate day fasting (ADF) as a healthy dietary pattern has been reported to improve brain functions and behaviors, but the effect of ADF on diabetes-related brain disorders and the potential mechanisms remain unclear.
Kaiyan Gong +10 more
doaj +1 more source
Urim: Large-Scale, Stochastic Symmetries [PDF]
, 2018 Many cyberneticists would agree that, had it not been for e-commerce, the investigation of redundancy might never have occurred. After years of essential research into Moore's Law, we demonstrate the visualization of architecture, demonstrates the ...
Torres, M. (Mary)
core
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Infrasonic observations of large-scale HE events [PDF]
, 1990 The Los Alamos Infrasound Program has been operating since about mid-1982, making routine measurements of low frequency atmospheric acoustic propagation. Generally, the authors work between 0.1 Hz to 10 Hz; however, much of the work is concerned with the
Davidson, Masha B. +3 more
core +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source