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Large-Scale Nonlinear Optimization

2006
Fast Linear Algebra for Multiarc Trajectory Optimization (Nicolas Berend, J. Frederic Bonnans, Julien Laurent-Varin, MounirHaddou, Christophe Talbot).- Lagrange Multipliers with Optimal Sensitivity Properties in Constrained Optimization (Dimitri P. Bertsekas).- n O(n^2) Algorithm for Isotonic Regression (Oleg Burdakov, Oleg Sysoev, Anders Grimvall ...
DI PILLO, Gianni, ROMA, Massimo
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Large-Scale Transcriptome Analysis

2017
Genomic variants identified to be linked with complex traits such as blood pressure are fewer in coding sequences compared to noncoding sequences. This being the case, there is an increasing need to query the expression of genes at a genome scale to then correlate the cause of alteration in expression to the function of variants regardless of where ...
David, Weaver   +2 more
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Neuromorphic Hardware, Large Scale

2014
A neuromorphic hardware system is an electronic system for information processing, based, to a certain degree, on the example of the biological nervous system. The operation of the whole system resembles the behavior of a network built from “neurons” and “synapses.” The degree of biological realism varies greatly between different research projects and
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Large-scale SAR analysis

Drug Discovery Today: Technologies, 2013
The analysis of structure–activity relationships (SARs) is a central task in medicinal chemistry. Traditionally, SAR exploration has concentrated on individual compound series. This conventional approach is complemented by large-scale SAR analysis, which puts strong emphasis on data mining and SAR visualization.
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Large-Scale Portfolio Optimization

Management Science, 1984
This paper describes a practical algorithm for large-scale mean-variance portfolio optimization. The emphasis is on developing an efficient computational approach applicable to the broad range of portfolio models employed by the investment community. What distinguishes these from the “usual” quadratic program is (i) the form of the covariance matrix ...
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Large-Scale Unconstrained Optimization

This work is a survey on the methods for large scale unconstrained optimization. Besides its own theoretical importance, the growing interest in the last years in solving problems with a larger and larger number of variables are arising very frequently from real world as a result of modeling systems with a very complex structure. In this paper the main
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Large Scale Paper Chromatography

Science, 1950
C, YANOFSKY, E, WASSERMAN, D M, BONNER
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LARGE SCALE COMPUTING

Non-Accelerator Astroparticle Physics, 2005
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