Results 201 to 210 of about 109,287 (258)

Accelerating Primary Screening of USP8 Inhibitors from Drug Repurposing Databases with Tree‐Based Machine Learning

Advanced Intelligent Discovery, EarlyView.
This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng, Sharon Ai Er Lam, Wei Chun Lim, Hannah Hui Min Toh, Shi Jun Ang   +4 more
wiley   +1 more source

Deformation characteristics of weakly cemented overburden in Western mining areas in China. [PDF]

Sci Rep
Zhang G, Zhang H, Li G, Chen J, Zhao L, Zhou G.   +5 more
europepmc   +1 more source

Mine Waste Disasters on the Zambian Copperbelt: Regulatory and Community Concerns. [PDF]

Environ Manage
Mukumba CP, Sishekanu M, Marais L.
europepmc   +1 more source

Multi-scale soil moisture dynamics in arid mined Loess Plateau arise from crack evolution and microstructure collapse. [PDF]

Sci Rep
Ma T, Tang F, Zhang F.
europepmc   +1 more source

Research on energy storage in coal mine goafs: geological model construction and application based on Nanshan Mine. [PDF]

Sci Rep
Feng M, Zhang B, Yang G, Wang Q.
europepmc   +1 more source

Overlooked deforestation from global mining activities in the 21st century. [PDF]

Nat Commun
Zhang X, Chen B, An J, Lin C, Gong P.
europepmc   +1 more source

Large-scale mining and social innovation

, 2016
openaire   +1 more source

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LSOMP: Large Scale Ordinance Mining Portal

2020 IEEE International Conference on Big Data (Big Data), 2020
We propose a novel scalable Web portal called LSOMP (Large Scale Ordinance Mining Portal) to analyze ordinances and their tweets (of the order of thousands and millions). It entails commonsense knowledge (CSK) and natural language processing (NLP), disseminating ordinance-tweet mining results via interactive graphics and Question Answering (QA).
Xu Du, Matthew Kowalski, Aparna S. Varde, Boxiang Dong   +3 more
openaire   +1 more source