Results 201 to 210 of about 1,318 (281)

Medical Malpractice Lawsuits Against Team Physicians in the National Football League Increased Between 1971 and 2020 But Remain Low Overall. [PDF]

Arthrosc Sports Med Rehabil
Littleford K, Arbon JJ, DeFoor MT, Cognetti DJ.   +3 more
europepmc   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

2-Rotund norms for unconditional and symmetric sequence spaces. [PDF]

Banach J Math Anal
Dilworth S, Kutzarova D, Motakis P.
europepmc   +1 more source

Computational Content of Large Cardinal Axioms

SÉRGIO DE ANDRADE, PAULO
openalex   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

Large-Scale Trade-Off Curve Computation for Incentive Allocation with Cardinality and Matroid Constraints [PDF]

Mingyang Zhou, Yihuan Lin, Gang Liu
openalex   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Longevity of Polish top-class athletes compared to other social elites and well-known people in the years 2001-2021. [PDF]

Int J Occup Med Environ Health
Śmigielski W, Małek Ł, Kwaśniewska M, Gajda R, Pawlak-Sobczak K, Korczak K, Cicha-Mikołajczyk A, Piwońska A, Piwoński J, Śmigielski J, Drygas W.   +10 more
europepmc   +1 more source

Real determinacy and real Blackwell determinacy (Interplay between large cardinals and small cardinals)

, 2011
Daisuke Ikegami
openalex   +1 more source