Results 31 to 40 of about 793 (236)
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan +1 more
wiley +1 more source
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar +7 more
wiley +1 more source
LARGE CARDINALS AS PRINCIPLES OF STRUCTURAL REFLECTION
AbstractAfter discussing the limitations inherent to all set-theoretic reflection principles akin to those studied by A. Lévy et. al. in the 1960s, we introduce new principles of reflection based on the general notion of Structural Reflection and argue that they are in strong agreement with the conception of reflection implicit in Cantor’s original ...
openaire +2 more sources
ABSTRACT Introduction The use of herbal medical preparation (HMP) is rising among pediatric oncology patients, often to manage treatment‐related symptoms. Their effectiveness remains uncertain, and the risk of herb–drug interactions is underestimated.
Orianne Mahot +6 more
wiley +1 more source
ABSTRACT Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened attention to imaging doses is necessary to minimize long‐term toxicity in survivors.
Parham Alaei +17 more
wiley +1 more source
Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall +2 more
wiley +1 more source
Rank-Based Family of Probability Laws for Testing Homogeneity of Variable Grouping
In order to test within-group homogeneity for numerical or ordinal variable groupings, we have introduced a family of discrete probability distributions, related to the Gini mean difference, that we now study in a deeper way. A member of such a family is
Manuel L. Esquível +4 more
doaj +1 more source
The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo +5 more
wiley +1 more source
TAMENESS FROM LARGE CARDINAL AXIOMS [PDF]
AbstractWe show that Shelah’s Eventual Categoricity Conjecture for successors follows from the existence of class many strongly compact cardinals. This is the first time the consistency of this conjecture has been proven. We do so by showing that every AEC withLS(K) below a strongly compact cardinalκis <κ-tame and applying the categoricity transfer ...
openaire +2 more sources
ABSTRACT Background Leukemia is the most common childhood cancer in Mexico, and acute lymphoblastic leukemia (ALL) is the most frequent subtype. Exposure to high concentrations of benzene has been associated with ALL incidence, particularly in urban areas. This study evaluated the relationship between distance to benzene emission sources and the number
Orlando Rivera Zurita +5 more
wiley +1 more source

