Results 91 to 100 of about 13,006,447 (294)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Large deviations and heterogeneities in driven or non-driven glassy systems
EPJ Web of Conferences, 2013 We give a short overview of the results for large deviations of dynamical quantities obtained for models of glassy systems. We introduce the paper with the study of kinetically constrained models (KCMs), first without external forcing.
Pitard Estelle
doaj +1 more source
Cyclic Esotropia: Surgical Treatment Results of Two Cases
Türk Oftalmoloji Dergisi, 2014 Cyclic esotropia is a rare form of strabismus characterized by alternating periods of esotropia and orthophoric (or almost orthophoric) eye position. Herein, we discuss two children with cyclic esotropia and their surgical treatment results.
Serpil Akar +4 more
doaj +1 more source
Large deviations theorems in nonparametric regression on functional data [PDF]
Comptes Rendus. Mathématique, 2011 In this Note we prove large deviations principles for the Nadaraya–Watson estimator of the regression of a real-valued variable with a functional covariate. Under suitable conditions, we show pointwise and uniform large deviations theorems.
openaire +2 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
ANALISIS PORTOFOLIO SAHAM LQ45 MENGGUNAKAN FUNGSI UTILITAS KUADRATIK
E-Jurnal Matematika, 2013 Utility function can use to give risk preference for investors who want to get the benefits gained meets investment targets. Quadratic utility functions on optimal portfolio is strongly influenced by the expected return and standard deviation.
KADEK FRISCA AYU DEVI +2 more
doaj +1 more source
Optimal investment and asymmetric risk for a large portfolio: a large deviations approach [PDF]
In this study, we propose a new method based on the large deviations theory to select an optimal investment for a large portfolio such that the risk, which is defined as the probability that the portfolio return underperforms an investable benchmark, is ...
Knight, John L. +2 more
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
A Large Deviation Principle at play in Large-Scale Structure cosmology [PDF]
, 2016 5 pages, 2 figuresWe present an application of Large Deviation Theory to the problem of structure growth on large-scale structure cosmology. Starting from gaussian distributed overdensities on concentric spherical shells, we show that a Large Deviation ...
Reimberg, Paulo, Bernardeau, Francis
core +3 more sources
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source