Results 101 to 110 of about 1,088,601 (319)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Nuclear Physics B, 2015 We consider a model of quantum-wire junctions where the latter are described by conformal-invariant boundary conditions of the simplest type in the multicomponent compactified massless scalar free field theory representing the bosonized Luttinger liquids
Krzysztof Gawȩdki, Clément Tauber
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Large Deviations and Sum Rules for Spectral Theory - A Pedagogical Approach [PDF]
, 2018 This is a pedagogical exposition of the large deviation approach to sum rules pioneered by Gamboa, Nagel and Rouault. We’ll explain how to use their ideas to recover the Szegő and Killip–Simon Theorems.
Breuer, Jonathan +2 more
core
Deep Inelastic Scattering on Ultracold Gases
Physical Review X, 2017 We discuss Bragg scattering on both Bose and Fermi gases with strong short-range interactions in the deep inelastic regime of large wave vector transfer q, where the dynamic structure factor is dominated by a resonance near the free-particle energy ℏω=ϵ_{
Johannes Hofmann, Wilhelm Zwerger
doaj +1 more source
Limits of large deviation theory in predicting transition paths of climate tipping events
, 2023 Reyk Börner +6 more
openalex +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Lee-Yang theory, high cumulants, and large-deviation statistics of the magnetization in the Ising model [PDF]
, 2020 Aydin Deger +2 more
openalex +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source