Results 101 to 110 of about 3,003 (261)

A White Paper on Advancing Long‐Acting Therapeutics for Maternal and Pediatric Health by Bridging Gaps in Clinical Research, Access and Regulation

Clinical Pharmacology &Therapeutics, EarlyView.
As use cases for long‐acting therapeutics expand across clinical indications, there is a critical need to ensure the inclusion of women who are pregnant or breastfeeding, infants and children—populations with a historical gap in the availability of interventions already approved for use in adults.
Moherndran Archary, Robert Bies, Osei Boateng, Rachel Daley, Pierre Gashema, Mili Karina, Emily Njuguna, Sharon Nachman, Nathaniel Nkrumah, Carolyne Odula, Andrew Owen, Ethel D. Weld, Prajith Venkatasubramanian, Adeniyi Olagunju, on behalf of the Community of Practice for Long‐acting Therapeutics for Maternal and Paediatric Health, Rana Abutaima, Dorothy Akongo, Abdulnaser Alsharaa, Moherndran Archary, Shakir Atoyebi, Benoit Bestgen, Robert Bies, Osei Boateng, Andrew Butler, Edmund Capparelli, Rachel Daley, Layla Davies, Joelle Dountio, Henry Enzama, Pierre Gashema, Katila George, Dan Hawcutt, Rene Holm, Patrick Gad Iradukunda, Elodie Jambert, Mili Karina, Linda Lewis, Grace Miheso, Sebastien Morin, Andrew Morrison, Sharon Nachman, Shadia Nakalema, Emily Njunga, Nathaniel Nkrumah, Carolyne Odula‐Obonyo, Brenda Okware, Adeniyi Olagunju, Andrew Owen, Martina Penazzato, Natella Rakhmanina, Mphako Brighton Ratlabyana, Rachel Scott, Kimberly Struble, Andre‐Marie Tchouatieu, Catherine Unsworth, Prajith Venkatasubramanian, Catriona Waitt, Ethel Weld, Janine Winterbottom, Leena Zino   +59 more
wiley   +1 more source

Enhancing hydrogen evolution reaction by harnessing bubble dynamics regulation: Principles, methods, and outlook

Droplet, EarlyView.
Bubble dynamics pose critical bottlenecks to hydrogen evolution reaction efficiency, causing active site isolation, increased ohmic resistance, and concentration overpotential, especially at high current densities. This review comprehensively summarizes passive and active bubble manipulation strategies, elucidates their underlying principles, and ...
Ziwei Guo, Chunhui Zhang, Yunxun Liu, Yi Han, Jinghang Pan, Lingyao Zhang, Chuanqi Nie, Yuejing Zhao, Kesong Liu, Cunming Yu, Lei Jiang   +10 more
wiley   +1 more source

Fish Scales: A Multifunctional Biomaterial from Nature

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Fish scales demonstrate nature's solution to impact protection through overlapping multilayered architecture. This biological design combines mineralized surfaces with collagen networks to achieve both flexibility and fracture resistance. The structural principles inspire advanced protective materials and biomedical implants, where damage tolerance ...
Liyao Dong, Xiaojie Sun, Xiguang Chen
wiley   +1 more source

Solar Fuels Via Methane Valorization: Thermochemical Pathways, Unified Metrics, and Techno‐Economic Perspectives

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
A first‐of‐its‐kind review benchmarks three solar methane valorization pathways with unified performance metrics for clean fuel production. Meeting global climate targets and sustainable energy demands requires carbon‐neutral fuels and innovative conversion pathways.
Muhammad Abdulmoez, Amjad Othman, Majid Linjawi, Amro Al‐Qutub   +3 more
wiley   +1 more source

Dimensional Engineering of Wet‐Spun MOF‐Based Woven Fabrics for Superior Electromagnetic Wave Absorption

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This work fabricated MOF‐based woven absorbing fabrics with dimensional engineering via a wet spinning strategy. The absorbing fabrics achieve a reflection loss of −51.47 dB at 2.9 mm, with an effective absorption bandwidth reaching 3.54 GHz. The absorbing fabrics can be freely bent, stretched, and folded, with individual fibers exhibiting a break ...
Zihao Yan, Liyuan Guan, Qing Liu, Junhao Lin, Jianyong Yu, Bin Ding, Zhaoling Li   +6 more
wiley   +1 more source

Glymphatic dysfunction couples with cortical excitation–inhibition imbalance in epilepsy: Evidence from Rasmussen encephalitis

Epilepsia, EarlyView.
Cong Fu et al. demonstrate that glymphatic system dysfunction is linked to enhanced inhibitory cortical activity using diffusion MRI and EEG. These findings highlight a mechanistic link between perivascular fluid dynamics and neuronal activity, suggesting a role for glymphatic function in maintaining cortical stability in epilepsy.
Cong Fu, Yujiao Yang, Pan Gong, Kun Lv, Yilin Liu, Chongyang Tang, Xiongfei Wang, Lixin Cai, Qingzhu Liu, Yuwu Jiang, Taoyun Ji, Guoming Luan   +11 more
wiley   +1 more source

Fully automated three‐dimensional deep learning‐based magnetic resonance imaging segmentation of brain cavities in epilepsy surgery

Epilepsia, EarlyView.
Abstract Objective There are several clinical and research applications for determining the amount of brain tissue resected after epilepsy surgery; however, manual segmentation of postoperative magnetic resonance imaging (MRI) is imprecise and time‐consuming.
Raphael Fernandes Casseb, Brunno Machado de Campos, Wallace Souza Loos, Marcelo Eduardo Ramos Barbosa, Marina Koutsodontis Machado Alvim, Gabriel Chagas Lutfala Paulino, Enrico Ghizoni, Francesco Pucci, Samuel Worrell, Clarissa Lin Yassuda, Roberto Medeiros de Souza, Lara Jehi, Fernando Cendes   +12 more
wiley   +1 more source

Mixing Behavior of Natural Gas and Hydrogen in a High‐Efficiency Vane (HEV) Static Mixer

Energy Science &Engineering, EarlyView.
Static mixers play a crucial role in the safe transport of hydrogen‐blended natural gas. Computational fluid dynamics (CFD) was employed to investigate the effects of structural parameters of the HEV static mixer on the mixing behavior and homogeneity of natural gas and hydrogen. The modeling approach was well validated against experimental data.
Xiang Zhou, Jun Zheng, Weiqing Xu, Dewen Kong, Yan Shi, Maolin Cai   +5 more
wiley   +1 more source

Technoeconomic Assessment of Wind Power Potential in the Vicinity of GolGohar Sirjan Mining and Industrial Company

Energy Science &Engineering, EarlyView.
Graphical abstract of wind energy study in the Vicinity of GolGohar Sirjan Mining and Industrial Company. ABSTRACT Wind energy is a central pillar of sustainable energy transition; however, its feasibility strongly depends on site‐specific wind regimes and economic conditions.
Hossein Amiri
wiley   +1 more source

Comparative Assessment and Benchmarking of Metaheuristic Algorithms for Dynamic Photovoltaic Array Reconfiguration Under Diverse Shading Environments

Energy Science &Engineering, EarlyView.
ABSTRACT The solar photovoltaic (PV) installations, which are essential for renewable energy systems, are vulnerable to partial shading, resulting in considerable power losses and operational inefficiencies. The dynamic reconfiguration of PV arrays has become an effective strategy to mitigate these effects by adaptively modifying the array topology to ...
Manoharan Premkumar, Ravichandran Sowmya, Jagarapu S. V. Siva Kumar, Mustafa Abdullah   +3 more
wiley   +1 more source