Results 71 to 80 of about 7,624,569 (302)

Gaussian variable neighborhood search for the file transfer scheduling problem [PDF]

open access: yesYugoslav Journal of Operations Research, 2016
This paper presents new modifications of Variable Neighborhood Search approach for solving the file transfer scheduling problem. To obtain better solutions in a small neighborhood of a current solution, we implement two new local search ...
Dražić Zorica
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Neighborhoods and mortality in Sweden: Is deprivation best assessed nationally or regionally?

open access: yesDemographic Research, 2018
Background: The association between neighborhood deprivation and mortality is well established, but knowledge about whether deprivation is best assessed regionally or nationally is scarce.
Daniel Oudin Åström   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Folder 8: LGRA, 1981-1982

open access: yes, 1981
Neighborhood Network of Dallas 1981 by Neighborhood Information and Action Services.
Neighborhood Information & Action Service
core   +1 more source

Primal-dual variable neighborhood search for the simple plant-location problem [PDF]

open access: yes, 2007
Copyright @ 2007 INFORMSThe variable neighborhood search metaheuristic is applied to the primal simple plant-location problem and to a reduced dual obtained by exploiting the complementary slackness conditions.
Brimberg, J   +3 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Researching Fairpark (Neighborhood Involvement Alliance)

open access: yes, 2006
In Spring 2006, a team of students from Prof. Luke Garrott\u27s Neighborhood Democracy class interviewed 66 Fairpark residents on their doorsteps to ask them about life in their neighborhood and city." A collection of survey data compiled into graphs and
Bernard, Charles
core  

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Very large‐scale neighborhood search

open access: yesInternational Transactions in Operational Research, 2000
AbstractNeighborhood search algorithms are often the most effective approaches available for solving partitioning problems, a difficult class of combinatorial optimization problems arising in many application domains including vehicle routing, telecommunications network design, parallel machine scheduling, location theory, and clustering.
R.K. Ahuja, J.B. Orlin, D. Sharma
openaire   +3 more sources

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