Results 231 to 240 of about 10,004,845 (289)

Topically Delivered Treg‐Attracting Microparticle‐Hydrogel Composites Recruit Regulatory T Cells and Limit Cardiac Injury After Severe Ischemia

Advanced Healthcare Materials, EarlyView.
CCL22‐releasing PLGA microparticles (MP) suspended in topically applied hydrogels (HEART) establish a sustained chemokine gradient at the injured myocardium. HEART recruits CCR4+ regulatory T cells, reduces infarct size and graft fibrosis, and improves cardiac function.
Matthew A. Borrelli, Alexis T. Reese, Jordan J. P. Warunek, Betsy Ann Varghese, Canxing Lin, Jeffery J. Baust, Brenda McMahon, Steven R. Little, Hēth R. Turnquist   +8 more
wiley   +1 more source

Bone Organoids Across the Development‐to‐Remodeling Continuum: From Tissue Formation to Functional Competence and Translation

Advanced Healthcare Materials, EarlyView.
Mineralization alone does not establish a mature bone organoid. This Review integrates biological foundations, materials design, adaptive remodeling, and translational validation through the development‐to‐remodeling continuum (DRC). By separating biological functions from the evidence supporting them, the framework exposes critical gaps in current ...
Xijie Tang, Haijia Xu, Xiangzhong Liu, Yi Yang, Zhanghua Li   +4 more
wiley   +1 more source

A Graph-Based Machine Learning Framework to Assign Empirical Interaction Parameters for Novel Molecules. [PDF]

J Comput Chem
Fu Y, Stroet M, O'Mara ML.
europepmc   +1 more source

Artemisinin‐Loaded Core‐Shell Microspheres Modulate Histone Lactylation to Remodel the Microenvironment for Cartilage Protection in Rheumatoid Arthritis

Advanced Healthcare Materials, EarlyView.
ART@PLGA@GH‐A microspheres are developed via microfluidic technology for intra‐articular delivery of artemisinin. The system remodels rheumatoid arthritis microenvironments by regulating metabolic and inflammatory disorders, reducing lactate‐driven histone lactylation and cellular senescence, while restoring cartilage homeostasis and protecting joint ...
Shijie Meng, Jianxin Li, Yuyang Luo, Yisi Liu, Feng Xing, Yingchen Ni, Fengyuan Zhang, Zhicheng Fan, Hua Xu, Weidong Zhang, Youhua Wang   +10 more
wiley   +1 more source

Health Atlas: Tutorial of a Visualization Tool and Data Resource for Place-Based Social and Structural Determinants of Health. [PDF]

J Med Internet Res
Oh DL, Kemper-McIsaac KE, Meltzer D, Brelsford E, Taylor K, Dixit DV, Nickerson A, Desai R, Shariff-Marco S, Lyles C, Gomez S, Pletcher MJ, DeRouen MC.   +12 more
europepmc   +1 more source

Beyond Presumptions: Toward Mechanistic Clarity in Metal‐Free Carbon Catalysts for Electrochemical H2O2 Production via Data Science

Advanced Materials, EarlyView.
Metal‐free carbon catalysts enable the sustainable synthesis of hydrogen peroxide via two‐electron oxygen reduction; however, active site complexity continues to hinder reliable interpretation. This review critiques correlation‐based approaches and highlights the importance of orthogonal experimental designs, standardized catalyst passports ...
Dayu Zhu, Hsi‐wen Wu, Xiao Wang, Jie Zhang   +3 more
wiley   +1 more source

Optimization of Farmland Cultivated Land Path Based on Hybrid Adaptive Neighborhood Search Algorithm. [PDF]

Sensors (Basel)
Lv H, Yao Z, Zhang T.
europepmc   +1 more source

Allostatic load in female cancer patients: a systematic review. [PDF]

Front Endocrinol (Lausanne)
Bu S, Zhang M, Tong H, Fu L, Ding Y.
europepmc   +1 more source

Optimization of Communication Tasks in an Energy-Efficient Swarm and the Spatial Distribution of Robots. [PDF]

Sensors (Basel)
Ijaz A, Haghbayan H, Nigussie E, Plosila J.   +3 more
europepmc   +1 more source