Results 41 to 50 of about 1,104,970 (268)

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

The existence of periodic solutions for a second order nonlinear neutral differential equation with functional delay

Electronic Journal of Qualitative Theory of Differential Equations, 2012
In this article we study the existence of periodic solutions of the second order nonlinear neutral differential equation with functional delay \[ \frac{d^{2}}{dt^{2}}x\left( t\right) +p\left( t\right) \frac{d}{dt}x\left( t\right) +q\left( t\right)
Abdelouaheb Ardjouni, Ahcene Djoudi
doaj   +1 more source

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann, Maike Wellbrock, Javier Louro, Arndt Borkhardt, Martin Schrappe, Claudia Trübenbach, Desiree Grabow, Cécile M. Ronckers, Joachim Schüz   +8 more
wiley   +1 more source

A boundary blow-up for sub-linear elliptic problems with a nonlinear gradient term

Electronic Journal of Differential Equations, 2006
By a perturbation method and constructing comparison functions, we show the exact asymptotic behaviour of solutions to the semilinear elliptic problem $$ Delta u -|abla u|^q=b(x)g(u),quad u>0 quadext{in }Omega, quad uig|_{partial Omega}=+infty ...
Zhijun Zhang
doaj  

Blow-up rates and uniqueness of entire large solutions to a semilinear elliptic equation with nonlinear convection term

Boundary Value Problems, 2018
In this paper, we analyze the blow-up rates and uniqueness of entire large solutions to the equation Δu=a(x)f(u)+μb(x)|∇u|q $\Delta u=a(x)f(u)+ \mu b(x) |\nabla u|^{q}$, x∈RN $x\in \mathbb{R}^{N}$ ( N≥3 $N\geq 3$), where μ>0 $\mu > 0$, q>0 $q > 0$ and a ...
Bo Li, Haitao Wan
doaj   +1 more source

Biphasic Clinical Course of Pediatric Cytomegalovirus‐Associated Immune Thrombocytopenia: Early Poor Treatment Response but Favorable Long‐Term Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad, Ohad Atia, Osama Tanous, Dafna Brik Simon, Michal Dvori, Miriam Cohen, Tracie A. Goldberg, Efraim Bilavsky, Joanne Yacobovich, Orna Steinberg‐Shemer   +9 more
wiley   +1 more source

Solution approaches to large shift scheduling problems [PDF]

RAIRO - Operations Research, 2008
Summary: This paper considers large shift scheduling problems with different shift start times and lengths, fractionable breaks and work stretch duration restrictions. Two solution approaches are proposed to solve the problems over a multiple-day planning horizon.
Monia Rekik, Jean-François Cordeau, François Soumis   +2 more
openaire   +3 more sources

Bone Mineral Density After Contemporary Treatment for Acute Lymphoblastic Leukaemia: A Matched Cross‐Sectional Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Reduced bone mineral density (BMD) has been reported in survivors of childhood and young adult acute lymphoblastic leukaemia (ALL); however, data from cohorts treated with contemporary protocols and including matched controls remain limited.
Karen Schow Jensen, Mette Tiedemann Skipper, Niels Holtum Birkebæk, Kjeld Schmiegelow, Thomas Leth Frandsen, Bente Langdahl, Rikke Beck Jensen, Asger Roer Pedersen, Christian Mølgaard, Liv Andrés‐Jensen, Birgitte Klug Albertsen   +10 more
wiley   +1 more source

Parents of Youth With Cancer Report on Their Psychosocial Care: iSTEPPP Survey Finds Alignment and Gaps With Standards

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The Standards for Psychosocial Care for Children with Cancer and Their Families guide the provision of comprehensive psychosocial care. Parallel to research characterizing implementation of the Standards from the perspective of providers, this study examines implementation of the Standards from the perspective of parents of youth ...
Emily M. Pariseau, Kimberly Buff, Michele A. Scialla, Kimberly S. Canter, Lori Wiener, Victoria Sardi‐Brown, Julia B. Tager, Kamyar Arasteh, Anne E. Kazak   +8 more
wiley   +1 more source

Bounded and large radially symmetric solutions for some (p,q)-Laplacian stationary systems

Electronic Journal of Differential Equations, 2012
This article concerns radially symmetric positive solutions of second-order quasilinear elliptic systems. In terms of the growth of the variable potential functions, we establish conditions such that the solutions are either bounded or blow up at ...
Adel Ben Dkhil, Noureddine Zeddini
doaj