Results 41 to 50 of about 805,278 (315)

Changes in Mycobacterium tuberculosis genotype families over 20 years in a population-based study in Northern Malawi. [PDF]

open access: yes, 2010
BACKGROUND: Despite increasing interest in possible differences in virulence and transmissibility between different genotypes of M. tuberculosis, very little is known about how genotypes within a population change over decades, or about relationships to ...
Houben, Rein M   +27 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

In Situ Synchrotron X-ray Micro-Diffraction Investigation of Elastic Strains in Laminated Ti-Al Composites

open access: yesMetals, 2021
Spatially resolved elastic strains in the bulk interior of a laminated Ti-Al metal composite were studied during in situ tensile loading at strains up to 1.66% by a synchrotron-based micro-diffraction technique, namely differential aperture X-ray ...
Tianbo Yu   +5 more
doaj   +1 more source

Development of a multilocus microsatellite typing approach for discriminating strains of Leishmania (Viannia) species.

open access: yes, 2009
A multilocus microsatellite typing (MLMT) approach based on the analysis of 15 independent loci has been developed for the discrimination of strains belonging to different Viannia species.
Espinosa, Diego   +10 more
core   +1 more source

Extensive genomic diversity and selective conservation of virulence determinants in enterohemorrhagic Escherichia coli strains of O157 and non O157 serotypes [PDF]

open access: yes, 2007
Background: Enterohemorrhagic Escherichia coli (EHEC) O157 causes severe food-borne illness in humans. The chromosome of O157 consists of 4.1 Mb backbone sequences shared by benign E.
Nougayrède, Jean-Philippe   +23 more
core   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

An analytical–numerical approach for the stability analysis of large strain thermo-elastoplastic material models

open access: yesArchives of Mechanics
The paper deals with the notion of stability for thermo-elastoplastic materials undergoing large strains. The stability analysis is performed by using the perturbation approach applied to a comprehensive material model derived in a thermodynamic format.
B. Wcisło   +3 more
doaj   +1 more source

Resource allocation accounts for the large variability of rate-yield phenotypes across bacterial strains

open access: yeseLife, 2023
Different strains of a microorganism growing in the same environment display a wide variety of growth rates and growth yields. We developed a coarse-grained model to test the hypothesis that different resource allocation strategies, corresponding to ...
Valentina Baldazzi   +4 more
doaj   +1 more source

Alvira : comparative genomics of viral strains [PDF]

open access: yes, 2007
The Alvira tool is a general purpose multiple sequence alignment viewer with a special emphasis on the comparative analysis of viral genomes. This new tool has been devised specifically to address the problem of the simultaneous analysis of a large ...
Fremez, Romain   +7 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

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