Results 161 to 170 of about 9,947,482 (276)
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Realistic atomic model for charge storage and charging dynamics of amorphous porous carbons. [PDF]
Peng J +5 more
europepmc +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Foreign object detection on photovoltaic panels based on DHLNet. [PDF]
Jin H, Li M, Lv X, Peng J.
europepmc +1 more source
Large-scale structure observations
Galaxy surveys are enjoying a renaissance thanks to the advent of multi-object spectrographs on ground-based telescopes. The last 15 years have seen the fruits of this experimental advance, including the 2-degree Field Galaxy Redshift Survey (2dFGRS; Colless M. et al., arXiv:0306581 (2003)) and the Sloan Digital Sky Survey (SDSS; York D.E.
openaire +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Thermal Management in Metal Hydride Hydrogen Storage Reactors: Mechanisms, Architectures, and Design Trade-Offs. [PDF]
Hou Q +8 more
europepmc +1 more source
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Unlocking the secrets of SARS-CoV-2 nsp3 by combining experiments with AlphaFold2 domain prediction. [PDF]
Edich M, Gao Y, Briggs DC, Thorn A.
europepmc +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source

