Results 31 to 40 of about 509,978 (288)

Factors determining low anterior resection syndrome after rectal cancer resection: A study in Thai patients

Asian Journal of Surgery, 2016
Background/Objective: Defective defecation function, also known as low anterior resection syndrome (LARS), is a common problem after surgical treatment of rectal cancer that has a detrimental effect on quality of life.
Patomphon Ekkarat, Teeranut Boonpipattanapong, Kasaya Tantiphlachiva, Surasak Sangkhathat   +3 more
doaj   +1 more source

Barriers to Using Legally Authorized Representatives in Clinical Research with Older Adults

Journal of Alzheimer's Disease Reports, 2023
Background: Older adults are at increased risk of cognitive impairments including Alzheimer’s disease dementia. Legally authorized representatives (LARs) can provide informed consent when a participant is no longer able to, but little is known about ...
Jessica Mozersky, Erin D. Solomon, Kari Baldwin, Matthew Wroblewski, Meredith Parsons, Melody Goodman, James M. DuBois   +6 more
doaj   +1 more source

The "McFL-LARS" Hybrid Technique: Fascia Lata Autograft and Synthetic Reinforcement for Combined Revision Anterior Cruciate Ligament Reconstruction and Lateral Extra-articular Tenodesis. [PDF]

Arthrosc Tech
Abstract Anterior cruciate ligament reconstruction using fascia lata autograft is a validated technique but remains limited by graft diameter or by the need to harvest a hamstring tendon. This report describes a novel hybrid approach, the “McFL‐LARS” hybrid technique, combining fascia lata autograft with a ligament advanced reinforcement system ...
de Geofroy B, Ogou A, Barbier O, Peras M, Teixeira P, Pessey LM, Choufani C.   +6 more
europepmc   +2 more sources

Biological and Biomechanical Evaluation of the Ligament Advanced Reinforcement System (LARS AC) in a Sheep Model of Anterior Cruciate Ligament Replacement: A 3-Month and 12-Month Study [PDF]

, 2013
PurposeThe purposes of this study were to assess tissue ingrowth within the Ligament Advanced Reinforcement System (LARS) artificial ligament (LARS AC; LARS, Arc sur Tille, France) and to study the biomechanical characteristics of the reconstructed knees
VIATEAU, Véronique, GUÉRARD, Sandra, Mignonney, Véronique, Manaserro, Mathieu, MITTON, David, MANASSERO, Mathieu, ANAGNOSTOU, Fani, MIGONNEY, Véronique, ANAGOSTOU, Fani   +8 more
core   +1 more source

Functional results after treatment for rectal cancer

Journal of Coloproctology, 2014
Introduction: With improving survival of rectal cancer, functional outcome has become in- creasingly important. Following sphincter-preserving resection many patients suffer from severe bowel dysfunction with an impact on quality of life (QoL) – referred
Katrine Jossing Emmertsen, Tina Yen-Ting Chen, Soren Laurberg   +2 more
doaj   +1 more source

Translation, validation and psychometric evaluation of the Persian (Farsi) version of the Low Anterior Resection Syndrome Score (LARS-P).

PLoS ONE, 2021
IntroductionLow anterior resection (LAR) for rectal cancer affects bowel function after the operation, causing a group of symptoms known as LAR Syndrome (LARS).
Mohammad Reza Keramati, Ali Abbaszadeh-Kasbi, Amir Keshvari, Seyed Mohsen Ahmadi-Tafti, Behnam Behboudi, Alireza Kazemeini, Mohammad Sadegh Fazeli   +6 more
doaj   +1 more source

Validation of the Vietnamese version of the low anterior resection syndrome score questionnaire [PDF]

Annals of Coloproctology
Purpose The aim of this study was to validate the low anterior resection syndrome (LARS) score questionnaire in the Vietnamese language among Vietnamese patients who underwent sphincter-preserving surgery for rectal cancer.
Tuong-Anh Mai-Phan, Vu Quang Pham
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

VALIDATION OF ROMANIAN VERSION OF LARS SCORE

Journal of Surgical Sciences, 2020
LARS is a widely spread complication in patients suffering from rectal cancer who had undergone a low anterior resection. Until recently it was very difficult to adequately quantify the impact that this syndrome has on patients’ quality of life. In 2012,
Octavian Andronic, Gerogiana Radu, Dan Nicolae Păduraru, Daniel Ion, Alexandra Bolocan, Sorin Mircea Oprescu   +5 more
doaj  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source