Results 41 to 50 of about 12,124 (305)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Análisis comparativo de El consentidor y el disentidor, de Bertolt Brecht, y Dogville, de Lars von Trier.

open access: yesTrasvases Entre la Literatura y el Cine, 2022
En el presente artículo se pretenden analizar los elementos literarios comunes que presentan las obras teatrales El consentidor y El disentidor, de Bertolt Brecht y la película Dogville, del director Lars von Trier con el teatro oriental.
María Hernández Rodríguez
doaj   +1 more source

Book review: female masochism in film by Ruth McPhee [PDF]

open access: yes, 2014
Ruth McPhee’s book takes work by Jane Campion and Lars von Trier and seeks to flip the common reductive and simplistic approaches to heterosexual female masochism and focus instead on the ambivalences and intricacies of this type of sexuality and ...
Matthews, Jodie
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

La sexualidad femenina en el cine de Lars von Trier. Caso concreto: Antichrist (2009) [PDF]

open access: yes, 2018
En el marco de una modalidad de trabajo que vincula investigación científica y análisis prácti co , se realiza un rastreo y revisión bibliográfica sobre la representación de la sexualidad femenina en el cine, con la ...
Otero Escudero, Sofía
core  

Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas   +39 more
wiley   +1 more source

6. Brecht/Von Trier. El distanciamiento en «Manderlay»

open access: yesAla Este, 2021
La teoría del distanciamiento de Brecht ha sido aplicada en el arte dramático de forma continua durante la segunda mitad del siglo XX por autores de distintas tendencias y escuelas.
Sergio Moreno Ramos
doaj  

Political Claustrophobia in Lars von Trier’s Europa and America Trilogies

open access: yesCINEJ Cinema Journal, 2018
This essay aims to trace the specific kind of political pessimism, that can be termed ‘political claustrophobia’ underlying the filmography of the Danish director Lars von Trier.
Özlem Denli
doaj   +1 more source

Reperfusion‐Dependent Outcomes After Endovascular Thrombectomy Stratified by NIHSS‐ASPECTS Clinical‐Core Mismatch

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This analysis evaluates the effect of successful reperfusion on functional outcomes after MT, stratified by admission National Institutes of Health Stroke Scale (NIHSS) and Alberta Stroke Program Early CT Score (ASPECTS) as surrogates for clinical‐core mismatch, using multicenter registry data.
Felix Schlicht   +53 more
wiley   +1 more source

A Voluntary End of Earth. Melancholia and Jean Améry

open access: yesCurrent Objectives of Postgraduate American Studies, 2015
This essay interrogates the semantics of finality in Lars von Trier’s Melancholia “(2011), in the light of Austrian theorist Jean Améry’s 1976 study On Suicide. A Discourse on Voluntary Death“.
Sebastian Thede
doaj   +1 more source

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