Results 241 to 250 of about 109,895 (311)

COX5A promotes cell progression and cisplatin‐resistance by alleviating mitochondrial dysfunction in head and neck squamous cell carcinoma

open access: yesPrecision Medical Sciences, EarlyView.
COX5A promotes cell progression and cisplatin‐resistance and alleviates mitochondrial dysfunction. ISG15 shows a reversing role with COX5A. Targeting the COX5A‐mediated mitochondrial metabolic pathway may offer a novel therapeutic approach to enhance cisplatin sensitivity in HNSCC.
Nannan Guo   +7 more
wiley   +1 more source

RNA degradomics and proteomics reveal the mechanism of dsProsβ1‐mediated proteasome targeting in Psylliodes chrysocephala

open access: yesPest Management Science, EarlyView.
RNA degradomics revealed dsProsβ1‐derived siRNA‐mediated mRNA cleavage events, mainly at uracil‐guanine and adenine‐adenine pairs. Proteasome inhibition via dsProsβ1 increased mitochondrial and cytoskeletal proteins while reducing translation‐related and mRNA‐binding proteins.
Doga Cedden   +3 more
wiley   +1 more source

SYN‐A, a naturally derived synergist, restores pyrethroid efficacy against cabbage stem flea beetle but negatively impacts its parasitoid Microctonus brassicae

open access: yesPest Management Science, EarlyView.
SYN‐A, a naturally derived synergist, inhibited key metabolic pathways associated with pyrethroid insecticide resistance in cabbage stem flea beetle (CSFB) and its parasitoid Microctonus brassicae. SYN‐A restored pyrethroid efficacy against resistant CSFB allowing up to 80% reduction in application rates.
Patricia A. Ortega‐Ramos   +2 more
wiley   +1 more source

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