Results 81 to 90 of about 33,987 (279)

Q&A: Cellular near death experiences-what is anastasis? [PDF]

open access: yes, 2017
Apoptosis is a form of programmed cell death that is carried out by proteolytic enzymes called caspases. Executioner caspase activity causes cells to shrink, bleb, and disintegrate into apoptotic bodies and has been considered a point of no return for ...
Montell, Denise J, Sun, Gongping
core   +1 more source

Understanding methods of wound debridement [PDF]

open access: yes, 2014
Autolytic debridement describes the body's natural method of wound-bed cleansing, helping it to prepare the wound bed for healing. In acute wounds, autolytic debridement occurs automatically and often does not require intervention, as during the ...
Broadus C   +5 more
core   +1 more source

Mitochondrial Enzymes Mimetic Ultrasmall Palladium Nanozymes Prevent Senescence and Neurodegeneration Through Metabolic Reprogramming

open access: yesAdvanced Science, EarlyView.
Simply constructed polyvinylpyrrolidone (PVP) modified palladium nanoparticles (PdP NPs) as cytochrome c oxidase (CcO) and superoxide dismutase (SOD) mimic are promising multifunctional nanoreactors to boost mitochondrial respiration chain function and refine homeostasis via regulation of mitochondrial dynamics and proteostasis sensor UPRmt, which ...
Wenshu Cong   +8 more
wiley   +1 more source

Oviposition site selection by the dengue vector Aedes aegypti and its implications for dengue control.

open access: yesPLoS Neglected Tropical Diseases, 2011
BackgroundBecause no dengue vaccine or antiviral therapy is commercially available, controlling the primary mosquito vector, Aedes aegypti, is currently the only means to prevent dengue outbreaks. Traditional models of Ae.
Jacklyn Wong   +4 more
doaj   +1 more source

Drosophila as a model system to study nonautonomous mechanisms affecting tumour growth and cell death [PDF]

open access: yes, 2018
The study of cancer has represented a central focus in medical research for over a century. The great complexity and constant evolution of the pathology require the use of multiple research model systems and interdisciplinary approaches.
Cordero, Julia B.   +2 more
core   +3 more sources

DTX3L Inhibits the EMT, Metastasis, and Stem‐Like Features of Gastric Cancer Through Promoting GSK‐3β Dependent SNAI1 Decay

open access: yesAdvanced Science, EarlyView.
This research identifies DTX3L as a critical tumor suppressor that inhibits epithelial‐mesenchymal transition (EMT), invasion and metastasis in gastric cancer. By functioning as an E3 ubiquitin ligase, DTX3L targets the master EMT regulator SNAI1 for GSK‐3β‐dependent proteasomal degradation.
Yang Chen   +7 more
wiley   +1 more source

Detrimental effects of geldanamycin on adults and larvae of Trichinella spiralis

open access: yesHelminthologia, 2016
Trichinellosis is a zoonotic disease affecting mainly the temperate regions. The treatment is a challenge for the physician, and the available therapy is far from ideal. Therefore, this work aimed to evaluate the effect of heat shock protein 90 inhibitor,
Othman A. A., Shoheib Z. S.
doaj   +1 more source

An Integrated Assessment of the Introduction of Lionfish (Pterois volitans/miles complex) to the Western Atlantic Ocean. [PDF]

open access: yes, 2003
Lionfish (Pterois volitans/miles complex) are venomous coral reef fishes from the Indian and western Pacific oceans that are now found in the western Atlantic Ocean.
Hare, Jonathan A., Whitfield, Paula E.
core  

Cell Segmentation Beyond 2D—A Review of the State‐of‐the‐Art

open access: yesAdvanced Intelligent Discovery, EarlyView.
Cell segmentation underpins many biological image analysis tasks, yet most deep learning methods remain limited to 2D despite the inherently 3D nature of cellular processes. This review surveys segmentation approaches beyond 2D, comparing 2.5D and fully 3D methods, analyzing 31 models and 32 volumetric datasets, and introducing a unified reference ...
Fabian Schmeisser   +6 more
wiley   +1 more source

UNVEILED THE LARVAL THERAPY AS ALTERNATIVE IN THE TREATMENT OF SKIN LESIONS: AN INTEGRATIVE REVIEW

open access: yesRevista de Pesquisa Cuidado é Fundamental Online, 2013
Objetivo: identificar nas evidências científicas da literatura quais os benefícios que a terapia larval proporciona aos pacientes com lesões de pele através de uma revisão sistemática da literatura, na modalidade de revisão integrativa.
Kauana Flores da Silva   +1 more
doaj   +5 more sources

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