Preclinical Evaluation of Ureidosulfamate Carbonic Anhydrase IX/XII Inhibitors in the Treatment of Cancers [PDF]
Carbonic anhydrases (CAs) are a family of enzymes involved in the pH regulation of metabolically active cells/tissues. Upregulation of the CAIX/XII isoforms is associated with hypoxic tumours and clinically linked with malignant progression, treatment ...
Gieling, Roben, Williams, Kaye J.
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This review article reports that quantification of hypoxic volumes using PET in the pre‐radiation therapy setting is of prognostic value and indicative of treatment response in non‐small cell lung cancer. Abstract Introduction Non‐small cell lung cancer (NSCLC) is the leading cause of cancer‐related death. Definitive treatment includes chemotherapy and
Carol Marks, Michelle Leech
wiley +1 more source
MicroRNA expression profiles in pediatric dysembryoplastic neuroepithelial tumors. [PDF]
© Springer Science+Business Media New York 2015Among noncoding RNAs, microRNAs (miRNAs) have been most extensively studied, and their biology has repeatedly been proven critical for central nervous system pathological conditions.
A Ranger +36 more
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Aerodynamic Analysis Of Voice In Persons With Laryngopharyngeal Reflux [PDF]
Objectives of the study: The individuals with laryngopharyngeal reflux are prone for aspiration of refluxed contents and so there is a need for aerodynamic evaluation in these individuals.
B, Radish Kumar, Bhat, Jayashree S. Bhat
core
ABSTRACT Objective With regulatory approval of HPV‐specific immunotherapy for recurrent respiratory papillomatosis (RRP) and growing experience with systemic bevacizumab, a management algorithm incorporating these medical treatments is warranted. Data Sources and Methods RRP Foundation (RRPF) Key Opinion Leaders offer a proposed management algorithm ...
Simon R. Best +17 more
wiley +1 more source
Identification alone versus intraoperative neuromonitoring of the recurrent laryngeal nerve during thyroid surgery: experience of 2034 consecutive patients [PDF]
Background: The aim of this study was to evaluate the ability of intraoperative neuromonitoring in reducing the postoperative recurrent laryngeal nerve palsy rate by a comparison between patients submitted to thyroidectomy with intraoperative ...
Calo', PIETRO GIORGIO +6 more
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Choice and Death: Analysis of Medical Assistance in Dying for Head and Neck Cancer in Ontario
The uptake of MAiD for head and neck cancer (HNC) has been steadily increasing since 2016, when MAiD first became available in Canada. Our study projects a substantial increase in the future use of MAiD for patients with HNC. As such, our health system needs to re‐evaluate and implement the necessary infrastructure to support the projected increase in ...
Tanika Curry +8 more
wiley +1 more source
Is there any Association between Helicobacter Pylori Infection and Laryngeal Carcinoma [PDF]
Objective: To investigate the possible role of Helicobacter pylori as a cause of squamous cell carcinoma of larynx in a case-control study in an otolaryngology ward at an academic university.
خوشباطن, منوچهر +3 more
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miRNA signature predittivo di metastasi linfonodali da carcinoma della laringe [PDF]
The discovery that miRNAs are frequently deregulated in tumours offers the opportunity to identify them as prognostic and diagnostic markers. The aim of this multicentric study is to identify a miRNA expression profile specific for laryngeal cancer.
Abate, T. +10 more
core +1 more source
Prognostic Value of Impaired Vocal Cord Mobility in T2N0 Glottic Cancer Treated With IMRT
T2N0M0 glottic cancers with impaired vocal cord mobility (VCM) have worse outcomes than T2N0M0 tumors with normal VCM, but still fare better than T3N0M0 disease. These findings support subdivision of T2 glottic cancer into T2a (normal VCM) and T2b (impaired VCM) in future TNM revisions.
Alexander Rühle +20 more
wiley +1 more source

