Results 11 to 20 of about 81,155 (383)

The clinical spectrum of SMA‐PME and in vitro normalization of its cellular ceramide profile

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1941-1952, December 2022., 2022
Abstract Objective The objectives of this study were to define the clinical and biochemical spectrum of spinal muscular atrophy with progressive myoclonic epilepsy (SMA‐PME) and to determine if aberrant cellular ceramide accumulation could be normalized by enzyme replacement.
Michelle M. Lee, Graeme S. V. McDowell, Darryl C. De Vivo, Daniel Friedman, Samuel F. Berkovic, Maria Spanou, Argirios Dinopoulos, Katheryn Grand, Pedro A. Sanchez‐Lara, Michelle Allen‐Sharpley, Jodi Warman‐Chardon, Alexander Solyom, Thierry Levade, Edward H. Schuchman, Steffany A. L. Bennett, David A. Dyment, Toni S. Pearson   +16 more
wiley   +1 more source

A phase II study of neoadjuvant capecitabine, oxaliplatin, and irinotecan (XELOXIRI) in patients with locally advanced rectal cancer

Annals of Gastroenterological Surgery, Volume 7, Issue 1, Page 81-90, January 2023., 2023
XELOXIRI neoadjuvant chemotherapy appears to be feasible and efficacious for patients with LARC. Although neoadjuvant XELOXIRI alone did not yield our expected pCR rate, the local recurrence rate, 3‐year DFS and measures of safety met current standards.
Chu Matsuda, Toshihiro Kudo, Yoshihiro Morimoto, Yoshinori Kagawa, Mitsuyoshi Tei, Yoshihito Ide, Norikatsu Miyoshi, Hidekazu Takahashi, Mamoru Uemura, Ichiro Takemasa, Taroh Satoh, Tsunekazu Mizushima, Kohei Murata, Yuichiro Doki, Hidetoshi Eguchi, Multicenter Clinical Study Group of Osaka, Colorectal Cancer Treatment Group (MSCSGO)   +16 more
wiley   +1 more source

Videolaryngoscopy Findings of the Vocal Health Program in Dysphonic Teachers in the Federal District, Brazil

International Archives of Otorhinolaryngology, 2022
Introduction The high phonatory demand required of teachers is a direct cause of the onset of vocal symptoms and of the development of laryngeal disorders.
Ronaldo Campos Granjeiro, Lorena Cássia de Carvalho Oliveira, Mirela Alves Dias, Cristiane Ferraz de Oliveira, Glauce Mara Gomes Ferreira Oliveira   +4 more
doaj   +1 more source

Extramedullary plasmacytoma of the larynx

International Archives of Otorhinolaryngology, 2012
Introduction: The extramedullary plasmocytoma is one of the localized forms of malignancy of the plasma cells, which has multiple myeloma main diagnosis. Its main site to the head and neck, but with a rare presentation in the larynx.
Pinto, José Antônio, Sônego, Thiago Branco, Artico, Marina Spadari, Leal, Carolina de Farias Aires, Bellotto, Silvana   +4 more
doaj   +3 more sources

Binary Logistic Regression Modeling of Voice Impairment and Voice Assessment in Iranian Patients with Nonlaryngeal Head-and-Neck Cancers after Chemoradiation Therapy: Objective and Subjective Voice Evaluation

Journal of Medical Signals and Sensors, 2023
Background: Laryngeal damages after chemoradiation therapy (RT) in nonlaryngeal head-and-neck cancers (HNCs) can cause voice disorders and finally reduce the patient's quality of life (QOL).
Sakineh Bagherzadeh, Daryoush Shahbazi-Gahrouei, Farhad Torabinezhad, Seied Rabi Mahdavi, Pedram Fadavi, Soraya Salmanian   +5 more
doaj   +1 more source

Vocal Fold Polyps: Literature Review

International Archives of Otorhinolaryngology, 2019
Introduction Vocal fold polyps are one of the most frequent benign laryngeal lesions, impacting the quality of life of those affected by them, primarily the vocal production.
Daniela de Vasconcelos, Adriana de Oliveira Camargo Gomes, Cláudia Marina Tavares de Araújo   +2 more
doaj   +1 more source

Pathological classification of equine recurrent laryngeal neuropathy [PDF]

, 2018
Recurrent Laryngeal Neuropathy (RLN) is a highly prevalent and predominantly left‐sided, degenerative disorder of the recurrent laryngeal nerves (RLn) of tall horses, that causes inspiratory stridor at exercise because of intrinsic laryngeal muscle ...
Draper, A C E, Piercy, R J
core   +1 more source

Extramedullary plasmacytoma: Tumor occurrence and therapeutic concepts—A follow‐up

Cancer Medicine, Volume 11, Issue 24, Page 4743-4755, December 2022., 2022
This paper provides an overview of the extramedullary plasmacytoma cases reported between 1999 and 2021. The global patients’ cohort and the current therapy options are compared to our previous report from 1999. Abstract Background Extramedullary plasmacytoma (EMP) is a solitary tumor consisting of neoplastic plasma cells, with very little to no bone ...
Adrian Holler, Iwona Cicha, Markus Eckstein, Marlen Haderlein, Marina Pöttler, Anja Rappl, Heinrich Iro, Christoph Alexiou   +7 more
wiley   +1 more source

Utility of Flexible Fiberoptic Nasolaryngoscopy in Assessment of Laryngeal Lesions Among Suspected Patients Living in Karachi, Pakistan

Journal of the Dow University of Health Sciences, 2019
Objective: To assess the utility of lexible iberoptic nasolaryngoscopy in diagnosing laryngeal lesions and identifying factors contributing to the development of serious laryngeal pathologies among suspicious patients.
Syeda Uzma Naqvi, Sadaf Zia, Muhammad Shuja Farrukh, Murtaza Ahsan Ansari, Atif Hafeez Siddiqui   +4 more
doaj   +1 more source

Triangular body-cover model of the vocal folds with coordinated activation of the five intrinsic laryngeal muscles [PDF]

, 2021
Poor laryngeal muscle coordination that results in abnormal glottal posturing is believed to be a primary etiologic factor in common voice disorders such as non-phonotraumatic vocal hyperfunction. Abnormal activity of antagonistic laryngeal muscles is hypothesized to play a key role in the alteration of normal vocal fold biomechanics that results in ...
arxiv   +1 more source