Results 71 to 80 of about 81,155 (383)

Targeting USP1 Potentiates Radiation‐Induced Type I IFN‐Dependent Antitumor Immunity by Enhancing Oligo‐Ubiquitinated SAR1A‐Mediated STING Trafficking and Activation

Advanced Science, EarlyView.
Targeting USP1 is identified as a strategy that significantly enhances type I IFN‐dependent innate immune response within the TME following radiotherapy. Mechanistically, USP1 inhibition facilitates STING trafficking from ER to Golgi by preserving K27‐linked oligo‐ubiquitination of SAR1A, thereby facilitating efficient activation of the dsDNA‐cGAS ...
Weilin Zhou, Yuxuan Zhao, Wenjing Qin, Weijian Wu, Chenyang Liao, Yiqiu Zhang, Xingli Yang, Xue Chen, Youqiao Wang, Yushan Kang, Jiaxin Wu, Jiaojiao Zhao, Junmin Quan, Xuecen Wang, Xianzhang Bu, Xin Yue   +15 more
wiley   +1 more source

Pencil‐beam scanning proton therapy for the treatment of glomus jugulare tumours

Journal of Medical Radiation Sciences, Volume 69, Issue 4, Page 456-462, December 2022., 2022
The rare locally destructive glomus jugulare tumours could be treated using pencil‐beam scanning proton therapy (an alternative to surgery). Proton therapy provides good local control and acceptable toxicity. This paper reports treatment outcomes, acute and early late toxicities of 12 patients with glomus jugulare tumours.
Jiří Kubeš, Vladimír Vondráček, Michal Andrlik, Matěj Navrátil, Silvia Sláviková, Daniel Klika, Alexandra Haas, Kateřina Dědečková, Kateřina Kopečková, Barbora Ondrová, Eliška Rotnáglová, Štěpán Vinakurau, Alexander Grebenyuk, Jozef Rosina   +13 more
wiley   +1 more source

Potential of a neural network in the diagnosis of laryngeal tumors [PDF]

Digital Diagnostics
BACKGROUND: Currently, artificial intelligence in the form of artificial neural networks is being actively implemented in a number of areas of our lives, including medicine.
Evgeniya A. Safyannikova, Andrey I. Kryukov, Natalya L. Kunelskaya, Pavel A. Sudarev, Svetlana G. Romanenko, Diana I. Kurbanova, Ekaterina V. Lesogorova, Ekaterina N. Krasil’nikova, Anastasiya A. Ivanova, Anton P. Osadchiy, Natalya G. Shevyrina   +10 more
doaj   +1 more source

Localizing the Recurrent Laryngeal Nerve via Ultrasound with a Bayesian Shape Framework [PDF]

arXiv, 2022
Tumor infiltration of the recurrent laryngeal nerve (RLN) is a contraindication for robotic thyroidectomy and can be difficult to detect via standard laryngoscopy. Ultrasound (US) is a viable alternative for RLN detection due to its safety and ability to provide real-time feedback.
arxiv  

MENSTRUAL INFLUENCE ON LARYNGEAL DISEASE [PDF]

The American Journal of the Medical Sciences, 1891
n ...
openaire   +1 more source

Accurate and Noninvasive Dysphagia Assessment via a Soft High‐Density sEMG Electrode Array Conformal to the Submental and Infrahyoid Muscles

Advanced Science, EarlyView.
A stretchable, breathable, large‐area high‐density sEMG (HD‐sEMG) electrode array is reported, which enables seamless integration to the complex surface of the submental and infrahyoid muscles to detect high‐fidelity HD‐sEMG signals during swallowing.
Weijie Hong, Lin Mao, Kai Lin, Chongyuan Huang, Yanyan Su, Shun Zhang, Chengjun Wang, Daming Wang, Jizhou Song, Zuobin Chen   +9 more
wiley   +1 more source

Factors associated with pathologic complete response following neoadjuvant chemoradiation and esophagectomy for carcinoma of esophagus and gastroesophageal junction

Journal of Surgical Oncology, Volume 127, Issue 1, Page 48-55, January 2023., 2023
Abstract Background and Objectives The aim of this study was to analyze factors associated with pathologic complete response (pCR) following neoadjuvant chemoradiation (NCRT) and esophagectomy for carcinoma of the esophagus (EC) and gastroesophageal junction (GEJ).
Syed Nusrath, Subramanyeshwar R. Thammineedi, Kalidindi Venkata Vijaya Narsimha Raju, Sujith C. Patnaik, Ajesh R. Saksena, Jaya Karthik, Madhunarayana Basude, Pavan Kumar J, Srijan Shukla, Vishal B. Rao, Kishore Kumar C, Swathi Gujjuru, Rohan Tewani, Tasneem Rushdie, Rashmi Sudhir, Lynette M. Smith, Chandrakanth Are   +16 more
wiley   +1 more source

The prosody and the music of the human speech [PDF]

, 2004
We propose the use of a self-oscillating dynamical system --the pre-Galileian clock equation-- for modeling the laryngeal tone. The parameters are shown to be the minimal control needed for generating the prosody of the human speech. Based on this model, we outline a peak delay detection algorithm for extracting the prosody of the real speech.
arxiv   +1 more source

MicroRNA-196a is a putative diagnostic biomarker and therapeutic target for laryngeal cancer. [PDF]

PLoS ONE, 2013
BACKGROUND: MicroRNA (miRNA) is an emerging subclass of small non-coding RNAs that regulates gene expression and has a pivotal role for many physiological processes including cancer development.
Koichiro Saito, Koji Inagaki, Takahiro Kamimoto, Yoko Ito, Toshiaki Sugita, Satoko Nakajo, Akira Hirasawa, Arifumi Iwamaru, Takashi Ishikura, Hideki Hanaoka, Keisuke Okubo, Tokio Onozaki, Takeru Zama   +12 more
doaj   +1 more source

Bronchoscopy, Imaging, and Concurrent Diseases in Dogs with Bronchiectasis: (2003-2014). [PDF]

, 2015
BackgroundBronchiectasis is a permanent and debilitating sequel to chronic or severe airway injury, however, diseases associated with this condition are poorly defined.ObjectiveTo evaluate results of diagnostic tests used to document bronchiectasis and ...
Byrne, BA, Johnson, EG, Johnson, LR, Kass, PH, Vernau, W   +4 more
core   +1 more source