Results 91 to 100 of about 397,949 (324)

Acidosis Forces Fatty Acid Uptake and Metabolism in Cancer Cells Regardless of Genotype

Advanced Science, EarlyView.
This study demonstrates that biological acidosis, commonly observed in tumors and ischemic conditions, actively promotes the protonation of fatty acids, thereby facilitating the uptake of their neutral forms. Consequently, the preference for lipid metabolism in acid‐exposed cells does not arise from genetic reprogramming that prioritizes lipids as the ...
Sébastien Ibanez, Maria Virginia Giolito, Sultan Al‐Siyabi, Kristian Serafimov, Florine Laloux, Emeline Dierge, Léo Aubert, Céline Guilbaud, Selena Kaye, Paula Varon, Dorothée Marchand, Hanne Vlieghe, Emmanuel Hermans, Caroline Bouzin, Davide Brusa, Christiani Andrade Amorim, Barabara Pachikian, Yvan Larondelle, Cyril Corbet, Chantal Dessy, Olivier Feron   +20 more
wiley   +1 more source

A rare case of ruptured liver metastases from a laryngeal cancer

Radiology Case Reports, 2021
Rupture of a metastatic liver tumor associated with laryngeal cancer is a very rare complication with no previous case in the literature. We present a case of ruptured liver metastases which was treated conservatively.
Inci Kizildag Yirgin, MD, Meltem Ekenel, MD, Duygu Has Simsek, MD, Bulent Acunas, MD   +3 more
doaj   +1 more source

A framework for identifying genotypic information from clinical records: exploiting integrated ontology structures to transfer annotations between ICD codes and Gene Ontologies [PDF]

, 2015
Although some methods are proposed for automatic ontology generation, none of them address the issue of integrating large-scale heterogeneous biomedical ontologies.
Hashemikhabir, Seyedsasan, Janga, Sarath Chandra, Xia, Ran, Xiang, Yang   +3 more
core   +1 more source

EGFR: New Insights on Its Activation and Mutation in Tumor and Tumor Immunotherapy

Advanced Science, EarlyView.
This review provides new perspectives on EGFR's activation, mutations, and their impact on tumor immunotherapy. It summarizes how EGFR is activated and the current EGFR targeting strategy, evaluates their clinical outcomes in combination with immunotherapy, highlighting differential responses in tumors with EGFR wild‐type and different mutants.
Yuanzhuo Gu, Hongchao He, Shilei Qiao, Yifan Shao, Lurong Wang, Zhengkui Zhang, Long Zhang, Fangfang Zhou   +7 more
wiley   +1 more source

Glottic-SubGlottic adenoid cystic carcinoma. A case report and review of the literature [PDF]

, 2013
Background: Malignant tumours of minor salivary glands are uncommon, representing only 2-4% of all head and neck cancers. In the larynx, minor salivary gland tumours rarely occur and constitute less than 1% of laryngeal neoplasm.
Conzo G, D'Errico G, Guerra G, Ilardi G, Motta G., Nunziata M, Riccitiello F, Siano M, Testa D, Vitale M   +9 more
core   +1 more source

Effect of Intraoperative Posture on Accurate Diagnostic Rate of Intraoperative Nerve Monitoring During Esophagectomy

Annals of Gastroenterological Surgery, EarlyView.
Adequate contact between the intubation tube and the vocal cord muscles is crucial for effective intraoperative nerve monitoring use during esophagectomy. Additionally, intraoperative posture significantly affects diagnostic outcomes and should be carefully considered.
Masami Yuda, Keita Takahashi, Yoshitaka Ishikawa, Takanori Kurogochi, Akira Matsumoto, Naoko Fukushima, Takahiro Masuda, Naoto Takahashi, Fumiaki Yano, Ken Eto   +9 more
wiley   +1 more source

Vocal fold schwannoma in a 13-year-old girl

Journal of the Scientific Society, 2020
Laryngeal neurogenic tumors are extremely rare clinical entity. It is a benign and slowly growing neoplasm. Schwannoma of the larynx often arises from the aryepiglottic fold and false vocal cord.
Santosh Kumar Swain, Smrutipragnya Samal, Somadatta Das, Rabindranath Padhy   +3 more
doaj   +1 more source

Prognostic Impact of Bone Mineral Density Reduction During Neoadjuvant Chemotherapy (NAC) in Patients Undergoing NAC Followed by Esophagectomy for Esophageal Cancer

Annals of Gastroenterological Surgery, EarlyView.
The association between BMD reduction during NAC and the worse prognosis remains unknown, although NAC followed by esophagectomy is a standard treatment for advanced ESCC. This study appeared that BMD massive reduction was an independent prognostic factor on OS (HR, 3.30; 95% confidence interval [CI], 1.69–6.55) and RFS (HR, 2.08; 95% CI, 1.19–3.63 ...
Kazuhide Sato, Keita Takahashi, Yoshitaka Ishikawa, Naoko Fukushima, Takahiro Masuda, Takanori Kurogochi, Masami Yuda, Akira Matsumoto, Kazuto Tsuboi, Yuichiro Tanishima, Fumiaki Yano, Ken Eto   +11 more
wiley   +1 more source

Assessment of quality of life in patients with laryngeal cancer: A review of articles.

Advances in Clinical and Experimental Medicine, 2018
This article presents a review of the medical literature published between 1994 and 2014 with the use of the PubMed database concerning quality-of-life instruments for head and neck cancer patients used to assess general well-being of patients with ...
M. Kolator, Patrycja Kolator, T. Zatoński   +2 more
semanticscholar   +1 more source

Influence of Facility Size on Perioperative Outcomes in Minimally Invasive Esophagectomy for 14 152 Patients With Esophageal Cancer Based on the Japanese National Clinical Database: A Multicenter Cohort Study

Annals of Gastroenterological Surgery, EarlyView.
This multicenter study investigated 14 152 minimally invasive esophagectomies (MIEs) using data from the Japanese National Clinical Database and showed a significantly lower operative mortality rate in high‐volume centers than in low‐volume centers. However, no differences in morbidity rates were found between facility sizes.
Taro Oshikiri, Hisateru Tachimori, Hiroaki Miyata, Yoshihiro Kakeji, Ken Shirabe   +4 more
wiley   +1 more source