Results 161 to 170 of about 397,949 (324)

Liquid Biopsies in Head and Neck Cancers: Recent Developments Across Biofluids, Analytes, and Molecular Features

Head &Neck, EarlyView.
ABSTRACT Background Head and neck cancers (HNCs) are too often diagnosed at advanced stages when outcomes are poor. Additionally, robust tools for the early detection of recurrence remain elusive. These gaps drive interest in so‐called liquid biopsy approaches for HNC detection, prognostication, and surveillance.
Patricia J. Brooks, Scott V. Bratman
wiley   +1 more source

Mortality of Laryngeal Cancer before and during the COVID-19 Pandemic

COVID
(1) Background: The interplay between coronavirus disease 2019 (COVID-19) and laryngeal cancer represents a substantial challenge for both patients and healthcare.
Riccardo Nocini, Giuseppe Lippi, Camilla Mattiuzzi   +2 more
doaj   +1 more source

Oncological Impact of Surgical Margin Status After Transoral Laser Microsurgery for Early Glottic Cancer

Head &Neck, EarlyView.
ABSTRACT Background Transoral laser microsurgery is a well‐established treatment for early glottic cancer. However, managing patients with close/positive margins remains debated. This study analyzes the relationship between resection margins and oncologic outcomes.
Sae Hatomi, Shuta Tomisato, Ken Kasahara, Hiroyuki Ozawa, Takeyuki Kono   +4 more
wiley   +1 more source

Poorly differentiated neuroendocrine carcinoma originating in the subglottic larynx: A case report with imm unohistochemical study

Clinical Case Reports
Key Clinical Message Laryngeal neuroendocrine carcinomas are the most common non‐squamous neoplasm of the larynx. Due to the rarity of the tumor, pathological diagnosis should be confirmed by immunohistochemistry.
Mahboobe Asadi, Milad Elyasi, Arvin Shahzamani, Saeedeh Miri   +3 more
doaj   +1 more source

Safety and Efficacy Findings From a Phase Ib/II Study of ASP‐1929 Photoimmunotherapy With Pembrolizumab in Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma

Head &Neck, EarlyView.
ABSTRACT Background ASP‐1929 photoimmunotherapy—cetuximab conjugated to IRDye 700DX and red light (690 nm) for localized drug activation—results in rapid, selective cell killing. Methods This phase Ib/II open‐label study evaluated ASP‐1929 photoimmunotherapy plus pembrolizumab in patients with recurrent/metastatic HNSCC (≥ 1 accessible lesion, PD‐L1 ...
David M. Cognetti, Joseph M. Curry, Jennifer Johnson, Michael Kwon, Shirley Y. Su, Francisco Civantos, Coral Olazagasti, Joseph Valentino, Susanne M. Arnold, R. Bryan Bell, Michael K. Gibson, Kyle Mannion, Kathryn M. Van Abel, Katharine A. Price, Haiying Dong, Amy H. Thorne, Toshiaki Suzuki, Ann M. Gillenwater   +17 more
wiley   +1 more source

Fuel for Recovery: Predicting G‐Tube Dependence in HPV‐Negative Operable HNSCC

Head &Neck, EarlyView.
ABSTRACT Background HPV‐negative head and neck squamous cell carcinoma (HNSCC) patients can face prolonged gastrostomy tube (g‐tube) dependence, affecting quality of life and delaying treatment. Existing models lack key health metrics like sarcopenia; this study develops a risk model to enhance preoperative assessment.
Marie‐Michelle McNicoll, Alex M. Mlynarek, Keith Richardson, Michael Hier, Nader Sadeghi, Anna Casola, Nathaniel Bouganim, Khashayar Esfahani, Christina Tsien, George Shenouda, Khalil Sultanem, Marco A. Mascarella   +11 more
wiley   +1 more source

Prediction of Recurrent Laryngeal Nerve Invasion in Thyroid Cancer by Ultrasound

Journal of Surgical Ultrasound
Assessing recurrent laryngeal nerve invasion is crucial for the accurate staging of thyroid cancer. This, in turn, determines the extent of surgery or whether active surveillance is appropriate.
Jin Hyang Jung, Eunji Kim, Byung Ju Kang
doaj   +1 more source

Radiotherapy versus open surgery versus endolaryngeal surgery (with or without laser) for early laryngeal squamous cell cancer. [PDF]

, 2014
Chudasama, Jessal, Dey, Paola, Kelly, Charles G Kelly, Loughran, Sean, McKenzie, Kenneth, Warner, Laura, Wright, Richard   +6 more
core   +1 more source

Retroperitoneal extramedullary hematopoietic pseudotumor in ataxia-telangiectasia. [PDF]

, 2018
Ataxia-telangiectasia confers a significant increase in the development of several cancer types, most commonly leukemia and lymphoma. However, as the natural history for these patients is evolving and their lifespan is increasing, there is the potential ...
Bateni, Cyrus P, Canter, Robert J, Darrow, Morgan A, Evans, Christopher P, Judge, Sean James, Plescia, Trevor A   +5 more
core  

Evaluating ChatGPT's recommendations for systematic treatment decisions in recurrent or metastatic head and neck squamous cell carcinoma: Perspectives from experts and junior doctors

International Journal of Cancer, EarlyView.
What's New? While artificial intelligence (AI) can potentially support clinical decision‐making in recurrent head and neck squamous cell carcinoma (HNSCC), its reliability and accuracy require extensive investigation. Here, the performance of ChatGPT‐4 as a decision‐support tool for staging and treatment planning in HNSCC was assessed. The tool was 83%
Danfang Yan, Lihong Wang, Liming Huang, Kejia Cheng, Yu Huang, Yangyang Bao, Xin Yin, Mengye He, Huiyong Zhu, Senxiang Yan   +9 more
wiley   +1 more source