Results 211 to 220 of about 114,700 (299)

Long non‐coding RNAs at the crossroads of inflammation, cancer and angiogenesis: Molecular mechanisms and their potential as therapeutic targets

British Journal of Pharmacology, EarlyView.
Long non‐coding RNAs (lncRNAs), a broad class of non‐protein‐coding RNAs, are characterized as new regulators of gene expression at the epigenetic, transcriptional, and post‐transcriptional level. Thus, lncRNAs are involved in the regulation of physiological processes and the development of human diseases and cancer by modulating proinflammatory ...
Charlie Leboff, Pamela Calle‐Mendoza, Maria Hatziapostolou, Christos Polytarchou   +3 more
wiley   +1 more source

Novel laryngeal preservation technique in postcricoid hypopharyngeal carcinoma: a case-series study. [PDF]

BMC Surg
Li X, Zhang X, Lin Y, Ma Y, Jiang Z, Lei D, Pan X, Liu J.   +7 more
europepmc   +1 more source

Myofibroblast‐Like CAFs in Metastatic Lymph Nodes Drive Tumor Stemness and Poor Prognosis in Head and Neck Cancer

Cancer Science, EarlyView.
Compared with PT‐CAFs, LN‐CAFs exhibited a myofibroblast‐like phenotype, enhanced tumor stemness‐promoting activity, and fibrosis‐, EMT‐, and hypoxia‐related transcriptomic signatures. LN‐CAF‐related gene signatures were independently associated with poor prognosis in head and neck squamous cell carcinoma.
Hiroyuki Hagiwara, Hideyuki Takahashi, Reika Kawabata‐Iwakawa, Miho Uchida, Hiroe Tada, Toshiyuki Matsuyama, Masaomi Motegi, Yuichi Tomidokoro, Kazuaki Chikamatsu   +8 more
wiley   +1 more source

Musashi‐1 Drives Radioresistance and Stemness in Head and Neck Squamous Cell Carcinoma via a Radioresistant FaDu Model

Cancer Science, EarlyView.
Fractionated irradiation generated radioresistant F‐IRR cells with enhanced CSC properties despite slower proliferation. MSI1 was strongly upregulated and functionally promoted stemness, tumorigenicity, and radiation resistance. JNK signaling acted upstream of MSI1, while JNK inhibition suppressed these malignant traits, identifying the JNK–MSI1 axis ...
Na‐Eun Kang, Chan‐Woong Jung, Yun‐Ju Kim, Sung‐Gil Chi, Jeong‐Yub Kim, Myung‐Jin Park   +5 more
wiley   +1 more source

Malnutrition predicts severe complications but not survival in laryngeal cancer surgery: a propensity-matched analysis. [PDF]

Front Nutr
Fang G, Zhu T, Lin Z, Yan M, Lin Z, Weng S, Bian C.   +6 more
europepmc   +1 more source

EPHX2 Loss Promotes CRC Migration via EET‐Dependent Chemokine Elevation and Mitochondrial Defect

Cancer Science, EarlyView.
Loss of EPHX2 promotes EET accumulation, which in turn enhances CXCL and ROS production, thereby promoting the migratory and invasive abilities of CRC cells. ABSTRACT Epoxide hydrolase 2 (EPHX2) is a key enzyme in fatty acid metabolism that metabolizes epoxyeicosatrienoic acids (EETs), lipid mediators involved in inflammation, angiogenesis, and ...
Jianjun Zhu, Jingjia Chang, Zhiyong Li, Jin Wu, Pengfei Yu, Jingjing Zheng, Li Li, Jia Tao, Hao Wu, Yintao Li, Ming Liu   +10 more
wiley   +1 more source

Five-year outcomes of transoral robotic surgery with or without neoadjuvant chemotherapy in laryngeal squamous cell carcinoma: a preliminary experience. [PDF]

Acta Otorhinolaryngol Ital
De Virgilio A, Meliante PG, D'Avino L, Kim SH.   +3 more
europepmc   +1 more source

Laryngeal Cancer Survival in Northern United Kingdom: A Multi‐Centre Retrospective Observational Study

Clinical Otolaryngology, EarlyView.
ABSTRACT Objectives Laryngeal cancer incidence has risen globally, yet survival outcomes have shown limited improvement over recent decades. This study evaluated contemporary outcomes across multiple centres in Northern UK and examined stage‐ and treatment‐specific survival. Design Multi‐centre retrospective observational study.
Amar Rajgor, Rhona Hurley, Catriona M. Douglas, Claire Paterson, James Moor, Shane Lester, Sara Sionis, Katherine Davies, James O’Hara, Gareth Inman, Terry Jones, David Winston Hamilton, Northern Head & Neck Alliance, Amarkumar Rajgor, Rhona Hurley, Catriona M. Douglas, Claire Paterson, James Moor, Shane Lester, Sara Sionis, Katherine Davies, James O'Hara, Gareth Inman, Terry Jones, David Winston Hamilton, Sarah Hill, Seamus O'Neill, Alison McLoughlin, Jemy Jose, Winson Wong, Michael Ho, Debbie Horne, Jarrod Homer, Matthew Kennedy, Emma Kinloch, Robert Metcalf, Iain Varley, Thomas Carroll, Sarah Healy, Helen Cocks, Michael Nugent, Leo Vassilou, Panos Kyzas, David Conway, John Greenman, Andrew Schache, Jason Fleming, Joanne Patterson, Keith Hunter, Paula Parvulescu, Rachel Brooker, Richard Shaw, Stephanie Meysner, Ola Rominiyi, Olena Mandrik   +54 more
wiley   +1 more source

The histopathological spectrum of laryngeal epithelial neoplasia. [PDF]

Acta Otorhinolaryngol Ital
Bellan E, Dei Tos AP, Sbaraglia M.
europepmc   +1 more source

Some Considerations on Laryngeal Neuroendocrine Neoplasms

Oncology and Therapy
openaire   +3 more sources