Results 211 to 220 of about 29,577 (264)

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review

British Journal of Pharmacology, Volume 183, Issue 9, Page 1779-1813, May 2026.
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos, Stavros Topouzis, Steve P. H. Alexander, Miriam M. Cortese‐Krott, Zsuzsanna Helyes, Kirill Martemyanov, Claudio Mauro, Nithyanandan Nagercoil, Reynold A. Panettieri Jr, Hemal H. Patel, Rainer Schulz, Barbara Stefanska, Gary J. Stephens, Nathalie Vergnolle, Xin Wang, Stephen Ward, Péter Ferdinandy   +16 more
wiley   +1 more source

Nine Metachronous Cancers Primarily Involving the Head and Neck: A Case Report. [PDF]

Cureus
Miyauchi A, Matsumoto S, Ito H, Hyodo M, Teshima M.   +4 more
europepmc   +1 more source

Therapeutic potential of mesenchymal stem cells in peripheral nerve injuries in horses

Equine Veterinary Education, Volume 38, Issue 5, Page 252-260, May 2026.
Summary Peripheral nerve injuries (PNI) in horses represent a significant clinical challenge, frequently associated with functional deficits and reduced athletic performance. Conventional therapeutic approaches, primarily based on anti‐inflammatory treatments and rehabilitation, offer limited efficacy, driving the search for innovative alternatives. In
L. V. de Oliveira Ferreira, R. Martins Amorim   +1 more
wiley   +1 more source

Risk factors for perioperative respiratory adverse events and unplanned intensive care admission in children with juvenile-onset recurrent respiratory papillomatosis undergoing carbon dioxide laser resection. [PDF]

World J Pediatr Surg
Yang X, Xu D, Zhan R, Lu Y.
europepmc   +1 more source

Computed Tomography Findings of Migrating Grass Awn Leading to Esophageal Perforation and Carotid Artery Erosion in a Dog

Veterinary Radiology &Ultrasound, Volume 67, Issue 3, May 2026.
ABSTRACT A 4‐year‐old male intact Kerry Blue Terrier presented with lethargy, pyrexia, intermittent cough, and a large, firm right ventral cervical mass. Contrast‐enhanced head and neck CT revealed a focally expansile, ill‐defined, mixed‐attenuation lesion with gas bubbles, suggestive of extensive cellulitis and abscessation, in close communication ...
Flavia Thaysa Vieira Freitag, Jennifer Marie Loewen, Gwo‐Yuan Yang, Yasmine Messiaen, Jasmine Yu Gu   +4 more
wiley   +1 more source

Papillary urothelial tumor of low malignant potential in a pediatric patient: case associated with Poland syndrome. [PDF]

Urol Case Rep
Arias K, Ceballos ML, Ordoñez JL, Medina EA, Duque M.   +4 more
europepmc   +1 more source

The Regulation and Function of Hippo/YAP Pathway in Cancer

The FASEB Journal, Volume 40, Issue 7, 15 April 2026.
Hippo/YAP pathway signaling plays critical roles in the progression of multiple cancer types. This review summarizes current knowledge of Hippo/YAP pathway regulation and function in cancer. We discuss the core components of the Hippo/YAP pathway; its crosstalk with other signaling pathways; regulation by non‐coding RNAs; roles of YAP signaling in ...
Chinmoy Ghosh, Ruchi Kakar, Seline Torkamboor, Yue Sun   +3 more
wiley   +1 more source

Global burden of respiratory system cancers in 2022 and 2050: incidence and mortality estimates from GLOBOCAN. [PDF]

BMC Cancer
Wang Y, Yu F, Qiu F, Fang K.
europepmc   +1 more source

Synthesis of Polyhydroxylated Pyrrolidinyl Analogs of Sugar Nucleotides. Experimental and Computational Studies on Their Interactions With GalNAC‐T's

ChemBioChem, Volume 27, Issue 7, 14 April 2026.
A multidisciplinary approach based on organic synthesis supported by quantum mechanical calculations, efficient phosphorylation methods, affinity studies using conventional techniques and saturation transfer difference nuclear magnetic resonance, together with molecular dynamics simulations, has enabled the preparation of nucleotide analogs with ...
Pedro Merino, Veronica Juste, Alejandro Montesa, Sandra Pereira, Sara Orta, Manuel Pedrón, Ana I. Jiménez, Sonsoles Martín‐Santamaría, Ramón Hurtado‐Guerrero, Ignacio Delso, Tomás Tejero   +10 more
wiley   +1 more source

Combined endoscopic and open frontolateral laryngectomy for glottic tumors involving the anterior commissure. [PDF]

Braz J Otorhinolaryngol
Haddad L, Ceccon FP, da Silva Souza LA, Ceccon BH, Pincelli JV, Aires MM.   +5 more
europepmc   +1 more source