Results 41 to 50 of about 29,577 (264)

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Management of laryngeal precancerous lesions [PDF]

, 2012
Objective: The identification of precancerous lesions is the basis of an early diagnosis, and of a treatment that allows, in the great part of cases, the preservation of organ functions.
De Stefano, A., Dispenza, C., Dispenza, F., Marchese, D., Martines, F.   +4 more
core   +1 more source

Cancer‐Associated Fibroblasts Functions as Multifunctional Architects of the Tumor Stroma and Represent Emerging Therapeutic Vulnerabilities

Advanced Science, EarlyView.
ABSTRACT Cancer‐associated fibroblasts (CAFs) are the predominant stromal components within the tumor microenvironment (TME), playing multifaceted roles in cancer progression through dynamic interactions with neoplastic and immune cells. Emerging evidence has revealed remarkable heterogeneity and plasticity of CAFs, which originate from diverse ...
Rujiao Liu, Lili Su, Shuiping Gao, Wenting Liu, Hongxia Wang   +4 more
wiley   +1 more source

Essential Updates 2024–2025: Surgical Strategy for Esophageal Cancer Toward a New Paradigm in the Era of Immunotherapy and Personalization

Annals of Gastroenterological Surgery, EarlyView.
This review summarizes key advances from 2024 to 2025 that are reshaping esophageal cancer surgery toward a strategy‐oriented, personalized paradigm through the integration of immunotherapy, population aging, and intelligent technologies. Adjuvant nivolumab after neoadjuvant chemoradiotherapy remains the only perioperative approach with durable benefit,
Shuichiro Oya, Koichi Yagi, Yoshifumi Baba   +2 more
wiley   +1 more source

Practical tips to reduce complication rate in thyroidectomy

Journal of Head & Neck Physicians and Surgeons, 2017
Introduction: Thyroid cancer is the most frequent endocrine neoplasm, and its incidence has been consistently rising during the last decades. Surgical treatment is the choice, but the complications can be truly devastating. Methods: The objective of this
Claudio Cernea, Lenine G Brandão, Flávio C Hojaij, Dorival De Carlucci, Felipe Vanderlei, Renato Gotoda, Ana K Leite, Marco A V Kulcsar, Leandro L Matos, Rogério A Dedivitis, Vergilius J F Araújo-Filho, Marcos R Tavares   +11 more
doaj   +1 more source

Extent of Lymph Node Dissection for cStage I Siewert Type I/II Cancers Based on Lymph Node Metastasis Risk Stratification

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim The optimal surgical strategy and extent of lymph node (LN) dissection for clinical Stage I (cStage I) adenocarcinoma of the esophagogastric junction (AEG) remain controversial. This study aimed to evaluate surgical outcomes and clarify the prevalence and distribution of LN metastasis according to tumor characteristics in cStage I Siewert ...
Masayoshi Terayama, Akihiko Okamura, Tomoyuki Irino, Naoki Takahashi, Jun Kanamori, Yu Imamura, Masaru Hayami, Motonari Ri, Souya Nunobe, Masayuki Watanabe   +9 more
wiley   +1 more source

Cidofovir for the Treatment of Recurrent Respiratory Papillomatosis: A Review of the Literature [PDF]

, 2005
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90089/1/phco.2005.25.7.977 ...
Abramson, Aduma, Andrei, Bishai, Blackledge, Bujia, Burgunda V. Sweet, Clarke, Crockett, De Clercq, Derkay, Doyle, Eicher, Endres, Gomez, Haglund, Ho, Johnson, Kashima, Kashima, Kramer, Leventhal, McCabe, Morgan, Mutz, Nadine Shehab, Norman D. Hogikyan, Osborne, Patel, Perkins, Phelps, Pransky, Pransky, Schnadig, Sedlacek, Shah, Shapiro, Smith, Tseng, Winnen   +39 more
core   +1 more source

Deep Learning‐Assisted Coherent Raman Scattering Microscopy

Advanced Intelligent Discovery, EarlyView.
The analytical capabilities of coherent Raman scattering microscopy are augmented through deep learning integration. This synergistic paradigm improves fundamental performance via denoising, deconvolution, and hyperspectral unmixing. Concurrently, it enhances downstream image analysis including subcellular localization, virtual staining, and clinical ...
Jianlin Liu, Rujia Liu, Xinyan Zhang, Xun Chen, Shuhua Yue   +4 more
wiley   +1 more source

DYNAMICS OF THE VENOUS BLOOD ACID-BASE BALANCE AND RELATIONSHIP BLOOD PH VS TUMOR IN LARYNGEAL CANCER PATIENTS

Сучасні медичні технології, 2020
The characteristic for most solid tumors cells is the intracellular alkalinization and acidification of the extracellular milieu and this pH gradient inversion (pHe < pHi) is associated with tumor proliferation, invasion, metastasis, aggressiveness, and ...
V. A. Kashirin, O. V. Khorolets, S. I. Andreev, A. A. Mikheev   +3 more
doaj   +1 more source

Incidence and Outcomes of Acute Implant Extrusion Following Anterior Cervical Spine Surgery. [PDF]

, 2017
STUDY DESIGN: Multi-institutional retrospective case series of 8887 patients who underwent anterior cervical spine surgery. OBJECTIVE: Anterior decompression from discectomy or corpectomy is not without risk.
Arnold, Paul M., Bumpass, David B., Bydon, Mohamad, Corriveau, Mark, Fehlings, Michael G., Fogelson, Jeremy L., Gokaslan, Ziya, Hart, Robert A., Hilibrand, Alan S., Lee, Sungho, Massicotte, Eric M., Mroz, Thomas E., Nassr, Ahmad, Pace, Jonathan, Riew, K. Daniel, Smith, Gabriel A., Steinmetz, Michael P.   +16 more
core   +2 more sources