Results 71 to 80 of about 14,436 (352)

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

open access: yesFEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran   +3 more
wiley   +1 more source

Influence of Experience on Performance of Individual Surgeons in Thyroid Surgery: Prospective Cross Sectional Multicentre Study [PDF]

open access: yes, 2012
Objective: To determine the association between surgeons’ experience and postoperative complications in thyroid surgery. Design: Prospective cross sectional multicentre study.
Bourdy, Stéphanie   +12 more
core   +3 more sources

DYNAMICS OF THE VENOUS BLOOD ACID-BASE BALANCE AND RELATIONSHIP BLOOD PH VS TUMOR IN LARYNGEAL CANCER PATIENTS

open access: yesСучасні медичні технології, 2020
The characteristic for most solid tumors cells is the intracellular alkalinization and acidification of the extracellular milieu and this pH gradient inversion (pHe < pHi) is associated with tumor proliferation, invasion, metastasis, aggressiveness, and ...
V. A. Kashirin   +3 more
doaj   +1 more source

An Euler-Bernoulli-Type Beam Model of the Vocal Folds for Describing Curved and Incomplete Glottal Closure Patterns [PDF]

open access: yesarXiv, 2023
Incomplete glottal closure is a laryngeal configuration wherein the glottis is not fully obstructed prior to phonation. In this work, we introduce an Euler-Bernoulli composite beam vocal fold (VF) model that produces qualitatively similar incomplete glottal closure patterns as those observed in experimental and high-fidelity numerical studies, thus ...
arxiv  

Advantages and limitations of navigation‐based multicriteria optimization (MCO) in selectively sparing pharyngeal constrictor muscles in head and neck radiotherapy treatment planning

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Sparing pharyngeal constrictor muscles (PCMs) during radiotherapy improves patient‐reported swallowing function. This study aimed to explore the feasibility of integrating knowledge‐based planning (KBP) with multicriteria optimization (MCO) in Eclipse v18.0 to selectively spare PCM, quantify the required trade‐off in prophylactic ...
Laura K. Howard   +3 more
wiley   +1 more source

Demonstration of an enhanced dosing pattern for debulking large and bulky unresectable tumors via differential hole‐size spatially fractionated radiotherapy

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose/objective We propose a novel lattice deployment for spatially fractionated radiotherapy (SFRT) treatments. In this approach, a larger diameter high‐dose sphere is centrally placed in the bulky tumor mass and surrounded by smaller diameter high‐dose spheres.
Joshua Misa   +2 more
wiley   +1 more source

Etiologies of Dysphonia in Patients Referred to ENT Clinics Based on videolaryngoscopy [PDF]

open access: yesIranian Journal of Otorhinolaryngology, 2014
Introduction: Laryngeal dysfunction may be divided into three categories; organic, neurologic and functional disorders. Dysphonia and hoarseness are the most common symptoms and, in some cases, the only signs of laryngeal dysfunction.
Keyvan Kiakojury   +3 more
doaj   +2 more sources

HEAT SHOCK PROTEIN 27 IN LARYNGEAL SQUAMOUS CELL CANCER TREATMENT

open access: yesСучасні медичні технології, 2020
Heat shock protein 27 (HSP27) belongs to a family of ATP-independent chaperones and plays a fundamental role in cell physiology in various disease states, including cancer. So, it was found that serum HSP27 levels were significantly increased in patients
O. V. Horolec   +2 more
doaj   +1 more source

3D Bioprinted Head and Neck Squamous Cell Carcinoma (HNSCC) Model Using Tunicate Derived Nanocellulose (NC) Bioink

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
A 3D bioprinted HNSCC model for use in anti‐cancer drug testing is established in proof‐of‐concept. The innovative tunicate‐derived nanocellulose hydrogel proved to be a viable alternative to gelatin‐based hydrogel, offering improved bioprintability for HNSCC model establishment.
Alexya Azhakesan   +7 more
wiley   +1 more source

Socioeconomic conditions and head and neck cancer: a systematic literature review [PDF]

open access: yes, 2011
O presente estudo teve como objetivo descrever as principais características dos estudos epidemiológicos que investigaram a associação entre condições socioeconômicas e câncer de cabeça e pescoço.
ANTUNES, José Leopoldo Ferreira   +1 more
core   +2 more sources

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