Higher order organizational features can distinguish protein interaction networks of disease classes: a case study of neoplasms and neurological diseases [PDF]
Neoplasms (NPs) and neurological diseases and disorders (NDDs) are amongst the major classes of diseases underlying deaths of a disproportionate number of people worldwide. To determine if there exist some distinctive features in the local wiring patterns of protein interactions emerging at the onset of a disease belonging to either of these two ...
arxiv
Bioinspired Nanoscale 3D Printing of Calcium Phosphates Using Bone Prenucleation Clusters
This study develops a bone‐bioinspired photoresin containing PNCs of calcium phosphates, enabling nanoscale precision via 2pp. This novel approach allows for 2D patterning and 3D nanostructuring of CaPs with intricate geometries. The technique offers unparalleled control over scaffold design and porosity, paving the way for advanced applications in ...
Iman Roohani+6 more
wiley +1 more source
Pencil‐beam scanning proton therapy for the treatment of glomus jugulare tumours
The rare locally destructive glomus jugulare tumours could be treated using pencil‐beam scanning proton therapy (an alternative to surgery). Proton therapy provides good local control and acceptable toxicity. This paper reports treatment outcomes, acute and early late toxicities of 12 patients with glomus jugulare tumours.
Jiří Kubeš+13 more
wiley +1 more source
A Hierarchical Transformer Encoder to Improve Entire Neoplasm Segmentation on Whole Slide Image of Hepatocellular Carcinoma [PDF]
In digital histopathology, entire neoplasm segmentation on Whole Slide Image (WSI) of Hepatocellular Carcinoma (HCC) plays an important role, especially as a preprocessing filter to automatically exclude healthy tissue, in histological molecular correlations mining and other downstream histopathological tasks.
arxiv
Optical Microfiber Biomedical Sensors: Classification, Applications, and Future Perspectives
This review delves deeply into the various types of optical microfiber biosensors, grounded firmly in their fundamental principles, and underscores their indispensable roles in pushing forward biomedical advancements. It examines the latest advancements, challenges faced by these biosensors in practical applications, future directions, breakthroughs ...
Lili Liang+5 more
wiley +1 more source
Abstract Background and Objectives The aim of this study was to analyze factors associated with pathologic complete response (pCR) following neoadjuvant chemoradiation (NCRT) and esophagectomy for carcinoma of the esophagus (EC) and gastroesophageal junction (GEJ).
Syed Nusrath+16 more
wiley +1 more source
Targeting USP1 is identified as a strategy that significantly enhances type I IFN‐dependent innate immune response within the TME following radiotherapy. Mechanistically, USP1 inhibition facilitates STING trafficking from ER to Golgi by preserving K27‐linked oligo‐ubiquitination of SAR1A, thereby facilitating efficient activation of the dsDNA‐cGAS ...
Weilin Zhou+15 more
wiley +1 more source
Comparative analysis of voice in diagnostics of T1 and T2 vocal cord carcinoma [PDF]
BACKGROUND: Dysphonia is the most frequent symptom of vocal cord carcinoma In the diagnostics of the disease subjective and objective methods of examination (acoustic analysis of a voice signal) and a laryngostroboscopy and aerodynamic examination are ...
Mitrović Slobodan M.
doaj +1 more source
Percutaneous Endoscopic Gastrostomy Tube Timing in Head and Neck Cancer Surgery
Objective To examine outcomes and complications in patients receiving a percutaneous endoscopic gastrostomy (PEG) tube on the same day of head and neck cancer (HNC) surgery versus later in hospitalization. Methods The 2003–2014 Nationwide Inpatient Sample was queried for patients undergoing ablative HNC procedures who had a PEG tube placed.
Corina Din‐Lovinescu+4 more
wiley +1 more source
Non-invasive diagnosis of upper airway malignancies based on the analysis of markers in exhaled air
The purpose of the study was to evaluate diagnostic capabilities of the gas analysis sensor device used for the study of exhaled gas samples obtained from patients with oropharyngeal and laryngeal cancers.Material and Methods. Exhaled gas samples from 31
D. E. Kulbakin+7 more
doaj +1 more source