Results 131 to 140 of about 153,455 (296)

Complete Pathologic Response to Neoadjuvant Pembrolizumab Captured on Intraoperative PET/CT: A Case Report and Exploratory Analysis

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Neoadjuvant immunotherapy is an emerging treatment for patients with head and neck cancer. Given the heterogeneity of response, novel methods of intraoperative tumor and margin assessment warrant investigation. Methods A 55‐year‐old male presented with a cT3N2c supraglottic squamous cell carcinoma with a combined positive score of 5.
Joaquin Austerlitz   +7 more
wiley   +1 more source

Epigenetic Dysregulation of Somatostatin Receptors (SSTR) 1–5 and Therapeutic Implications in Neuroendocrine and Non‐Neuroendocrine Malignancies

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Somatostatin receptors (SSTR) mediate the antiproliferative, antisecretory, and proapoptotic effects of somatostatin and its synthetic analogs. Their surface expression on neuroendocrine tumor (NET) cells is required for somatostatin analog therapy and radiopharmaceutical therapy (RPT).
Neeraj Kumari   +10 more
wiley   +1 more source

T2 glótico: Controversias

open access: yesRevista Cubana de Medicina, 2002
El cáncer glótico precoz en su categoría T2 es motivo actual de controversias debido a su diversidad clínica y evolutiva. La cirugía como tratamiento inicial trata de desplazar a la radioterapia del lugar que históricamente ha ocupado. Con el objetivo de
Luis Ferbeyre Binelfa   +4 more
doaj  

Optimising hypoxia PET imaging and its applications in guiding targeted radiation therapy for non‐small cell lung cancer: a scoping review

open access: yesJournal of Medical Radiation Sciences, Volume 72, Issue 1, Page 106-118, March 2025.
This review article reports that quantification of hypoxic volumes using PET in the pre‐radiation therapy setting is of prognostic value and indicative of treatment response in non‐small cell lung cancer. Abstract Introduction Non‐small cell lung cancer (NSCLC) is the leading cause of cancer‐related death. Definitive treatment includes chemotherapy and
Carol Marks, Michelle Leech
wiley   +1 more source

Transoral Robotic Surgery in Head and Neck Oncology: A Scoping Review of Evidence, Technological Advancements, and Future Trajectories

open access: yesJournal of Surgical Oncology, EarlyView.
ABSTRACT Robotic surgery has transformed head and neck cancer (HNC) treatment. This scoping review synthesizes evidence on transoral robotic surgery (TORS), focusing on applications, limitations, and future directions. Following PRISMA‐ScR guidelines, this review used the PCC framework (Population: HNC patients; Concept: technological advancements ...
Anna Luíza Damaceno Araújo   +6 more
wiley   +1 more source

LINC01605 Predicts the Poor Prognosis of Non‐Small Cell Lung Cancer and Promotes Chemotherapy Resistance by Regulating miR‐7111‐5p/ELK1

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Non‐small cell lung cancer (NSCLC) is characterized by high incidence, mortality, and poor patient prognosis, with chemotherapy resistance being a common challenge. This research intends to identify key molecules involved in NSCLC and elucidate the regulatory role of the LINC01605/miR‐7111‐5p/ELK1 axis in chemotherapy resistance. LINC01605 and
Fang Zhang   +4 more
wiley   +1 more source

Heterogeneity Analyzed by CT‐Based Habitat Analysis for Clinical Management of Cancers: A Narrative Review

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Tumors are highly heterogeneous, and whole‐lesion radiomics analysis is a popular method for extracting texture features that reflect this heterogeneity, which can be used to build models for cancer diagnosis, staging, therapy response evaluation, and prognosis prediction.
Yang Zhang   +2 more
wiley   +1 more source

Clonal Composition of Human Adrenocortical Neoplasms [PDF]

open access: yes, 1994
The mechanisms of tumorigenesis of adrenocortical neoplasms are still not understood. Tumor formation may be the result of spontaneous transformation of adrenocortical cells by somatic mutations.
Travis, W.   +7 more
core  

Thyroid Cartilage Reconstruction With Titanium Mesh in Advanced Papillary Thyroid Carcinoma

open access: yesThe Laryngoscope, EarlyView.
We report the first case of titanium mesh reconstruction of the thyroid cartilage following resection of papillary thyroid carcinoma with preservation of the laryngeal mucosa. This technique provided excellent functional outcomes while maintaining oncologic resection in a patient with locally advanced disease.
Anna Christina Clements   +5 more
wiley   +1 more source

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