Results 51 to 60 of about 40,099 (251)

Diagnostic Accuracy and Safety of Endoscopic – Guided Office-Based Biopsies for Laryngeal and Pharyngeal Lesions at St. Luke’s Medical Center

Philippine Journal of Otolaryngology Head and Neck Surgery
 Objective: To determine the sensitivity, specificity, positive predictive value, negative predictive value and safety of endoscopic guided office-based biopsies (OBB) in diagnosing laryngeal and pharyngeal neoplasms at the St.
Diana Fernandez, Ronaldo Soriano
doaj   +1 more source

A Cross-Sectional Study on Histopathology of Laryngeal Lesions in a Tertiary Care Center

Online Journal of Health & Allied Sciences, 2023
Laryngeal lesions can be benign, premalignant, or malignant. Patient history, clinical symptoms, and indirect laryngoscopy with a rigid or flexible fibre optic scope and stroboscopy can identify vocal nodules and polyps.
Priya K, Adithya V
doaj  

Positive Histopathological Margins: Are They Always Associated with Tumor Recurrence in Early Glottic Carcinoma?

Iatreia, 2023
Introduction: Squamous cell carcinoma of the larynx is one of the most common neoplasms in the head and neck region. In its early stages, it is characterized by a favorable oncological prognosis, leading to a management approach that focuses not only on ...
Maria Manuela Chemas-Vélez, Luis Humbert Jimenez-Fandiño, María Alejandra Díaz-Oliveros, Diana Carolina Bohórquez-Quintero   +3 more
doaj   +1 more source

Treatment of head and neck cancer with photodynamic therapy: results after one year [PDF]

, 2007
Photodynamic therapy (PDT) is a new and promising treatment modality for the treatment of malignant disease. This paper reports the preliminary experience of our group in the use of this therapy for the treatment of tumours arising in the head and neck ...
DeJode, ML, Dilkes, MG, Gardiner, Q, Kenyon, GS, McKelvie, P   +4 more
core   +1 more source

Adult Rhabdomyoma of the Larynx

International Archives of Otorhinolaryngology, 2013
Introduction Rhabdomyoma is a rare benign tumor derived from skeletal muscles. Laryngeal rhabdomyomas are even rarer, with only approximately 40 reported cases in world literature. Laryngeal rhabdomyomas usually are seen as masses covered by mucosa. They
Márcia Monteiro Pinho, Jair de Carvalho e Castro, Rosana Grandelle Ramos   +2 more
doaj   +1 more source

Follicular nodules (Thy3) of the thyroid: is total thyroidectomy the best option? [PDF]

, 2014
BACKGROUND: Identification of the best management strategy for nodules with Thy3 cytology presents particular problems for clinicians. This study investigates the ability of clinical, cytological and sonographic data to predict malignancy in ...
CALO', PIETRO GIORGIO, ERDAS, ENRICO, Medas F, NICOLOSI, ANGELO, Pisano G, Podda F, Santa Cruz R   +6 more
core   +1 more source

Neutrophil Extracellular Trap Reprograms Cancer Metabolism to Form a Metastatic Niche Promoting Non‐Small Cell Lung Cancer Brain Metastasis

Advanced Science, EarlyView.
This study mainly combines spatial/single‐cell transcriptomics and metabolomics to reveal LOX+ Malig‐5 as NSCLC brain metastasis‐initiating cells, forming a niche with NET‐releasing neutrophils via the NET‐KRT10 axis. The metastatic niche is involved with metabolic reprogramming, with palmitic acid serving as a key metabolite.
Bo Chen, Karrie M. Kiang, Fangkun Liu, Chuntao Li, Xizhe Li, Chen Weiwei, Xin Fu, Gelei Xiao, Jingyi Sun, Erhan Da, Junbo Liao, Hongshu Zhou, Li Meng, Li Zhou, Tao Song, Longbo Zhang, Gilberto Ka‐Kit Leung, Liyang Zhang   +17 more
wiley   +1 more source

A comparison of attitudes to laryngeal cancer treatment outcomes: a time trade-off study [PDF]

, 2017
Design: Time trade-off choice experiment. Setting: Two large head and neck cancer centres. Participants: Patients who have received treatment for head and neck cancer and members of the head and neck cancer multidisciplinary team.
Bins, Janneke, Blanchford, Hannah, Hamilton, David W., McMeekin, Peter, Paleri, Vinidh, Pedersen, Ami, Thomson, Richard G., Wilson, Janet   +7 more
core   +2 more sources

De Novo Gene Transcription of Connexin Mediates Cytoplasmic Fluid Exchange and Flocking Transitions in Physiological and Cancerous Epithelial Systems

Advanced Science, EarlyView.
EGF‐induced de novo transcription of connexins Cx26 and Cx31 promotes flocking behavior that fluidizes epithelia and enables coordinated collective migration. Connexin‐driven cytoplasmic exchange mechanistically links growth‐factor signaling to invasive dynamics.
Hind Abdo, Leonardo Barzaghi, Yuan Shen, Edoardo Bellini, Emanuele Martini, Serena Magni, Sara Barozzi, Fabrizio Orsenigo, Dario Parazzoli, Galina V. Beznoussenko, Jasmin Di Franco, Fabian Krautgasser, Jasmin Kaivola, Mario Cinquanta, Alessandro Lazzarin, Sara Sigismund, Johanna Ivaska, Roberto Cerbino, Giorgio Scita   +18 more
wiley   +1 more source

Smoking‐Induced STC2+ Tumor Cells Drive Tumor‐Vascular Crosstalk in Laryngeal Squamous Cell Carcinoma via Spatial and Single‐Cell Transcriptomics

Advanced Science, EarlyView.
This study identifies a smoking‐induced mechanism in LSCC whereby nicotine activates the CHRNA5–JAK2/STAT3 axis to drive STC2 transcription. STC2 upregulates TGFBI, which interacts with endothelial ITGA5 to regulate vascular permeability and promote metastasis.
Yujie Shen, Lianchong Gao, Qiang Huang, Liang Zhou, Chengzhi Xu, Chunping Wu   +5 more
wiley   +1 more source