Results 61 to 70 of about 13,622 (192)

Spatial Transcriptomics Unveils Landscape of Resistance to Concurrent Chemo‐Radiotherapy in Hypopharyngeal Squamous Cell Carcinoma: The Role of SPP1+ Macrophages

open access: yesCancer Medicine, Volume 15, Issue 1, January 2026.
ABSTRACT Background Hypopharyngeal squamous cell carcinoma (SCC) is an aggressive malignancy with a poor prognosis, particularly in advanced stages. Concurrent chemoradiotherapy (CCRT) is frequently employed to preserve the larynx, but resistance to CCRT remains a significant clinical challenge.
Jungyoon Ohn   +6 more
wiley   +1 more source

Validety of total laryngectomy Under local anaesthesia

open access: yesمجله كليه طب الكندي, 2012
BackgroundCarcinoma of the larynx represent 10% of head & neck malignancies. The treatment of advanced carcinoma of larynx may include partial or total laryngectomy, with or without laser , radiotherapy,and or chemotherapy .
Thamir M. Al-rubeai   +2 more
doaj   +2 more sources

An influence of some factors on the logopedic rehabilitation of patients after laryngectomy with tracheoesophageal bypass and voice prosthesis

open access: yesОпухоли головы и шеи, 2016
Tracheoesophageal bypass with endoprosthesis is one of the most important approaches for surgical ways of voice restoration after laryngectomy. Within after-surgery rehabilitation logopedic techniques may be practiced successfully for the patients ...
E. V. Kosova, T. A. Petrova
doaj   +1 more source

Reconstructive Options During Nonfunctional Laryngectomy [PDF]

open access: hybrid, 2020
Derek Escalante   +4 more
openalex   +1 more source

Predicting Local Recurrence in T3 Laryngeal Squamous Cell Carcinoma: An Analysis of Tumor Volume and Cartilage Invasion Prior to Radiotherapy

open access: yesCancer Medicine, Volume 15, Issue 1, January 2026.
ABSTRACT Introduction Patients with T3 laryngeal squamous cell carcinoma (LSCC) face a high risk of local recurrence after chemoradiotherapy (CRT) or radiotherapy (RT). This study examines whether tumor volume and inner cortex cartilage invasion (ICCI) predict local recurrence and survival.
Rasmus Blomkvist   +6 more
wiley   +1 more source

Late-term Effects of Surgery on Nasal Functions in Patients who Underwent Total Laryngectomy Surgery

open access: yesInternational Archives of Otorhinolaryngology, 2017
Introduction There is a common opinion that losing airway functions in total laryngectomy patients cause changes in nasal physiological rates. Studies conducted to review the subject present gaps, especially in terms of objective measurements.
Deniz Karaoglu   +3 more
doaj   +1 more source

CO2 Laser Division of Neo-Vallecula Improves Dysphagia in the Postlaryngectomy Patient: A Case Series and Review of the Literature

open access: yesCase Reports in Otolaryngology, 2020
Objectives. To review the literature on neo-vallecula diagnosis and management and to report our findings regarding 3 patients who developed neo-vallecula in the context of free-flap pharyngeal reconstruction following total laryngectomy. Methods.
Mohamad Z. Saltagi   +3 more
doaj   +1 more source

Oncological Impact of Surgical Margin Status After Transoral Laser Microsurgery for Early Glottic Cancer

open access: yesHead &Neck, Volume 48, Issue 1, Page 99-105, January 2026.
ABSTRACT Background Transoral laser microsurgery is a well‐established treatment for early glottic cancer. However, managing patients with close/positive margins remains debated. This study analyzes the relationship between resection margins and oncologic outcomes.
Sae Hatomi   +4 more
wiley   +1 more source

Management of Retropharyngeal Lymph Node Metastases in Thyroid Cancer

open access: yesHead &Neck, Volume 48, Issue 1, Page 237-245, January 2026.
ABSTRACT Background Retropharyngeal lymph node (RPLN) metastases in thyroid cancer are rare, with optimal management underreported. Methods Retrospective study of consecutive thyroid cancer patients with RPLN metastases treated at MD Anderson Cancer Center between 2000 and 2024.
Isabelle Fournier   +19 more
wiley   +1 more source

Primary Head and Neck Histiocytic Sarcoma of the Oropharyngeal Posterolateral Wall: A Case Report

open access: yesThe Laryngoscope, Volume 136, Issue 1, Page 240-242, January 2026.
Histiocytic sarcoma (HS) is a rare and aggressive malignancy, particularly uncommon in the head and neck region. This report describes the case of a 67‐year‐old male with HS originating from the oropharyngeal posterolateral wall, treated successfully with transoral CO2 laser excision and adjuvant proton radiotherapy.
Michael Dalè   +8 more
wiley   +1 more source

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