Results 51 to 60 of about 21,161 (260)

A methylation-phosphorylation switch controls EZH2 stability and hematopoiesis

eLife
The Polycomb Repressive Complex 2 (PRC2) methylates H3K27 to regulate development and cell fate by transcriptional silencing. Alteration of PRC2 is associated with various cancers.
Pengfei Guo, Rebecca C Lim, Keshari Rajawasam, Tiffany Trinh, Hong Sun, Hui Zhang   +5 more
doaj   +1 more source

Desaprendiendo de las vegas.

Astrágalo. Cultura de la arquitectura y la ciudad, 2001
El modelo arquitectónico y urbano de las Vegas como instrumento eficaz de la industria del turismo y el consumo de masas, pone en manifiesto un concepto civilizatorio y comunicacional propiamente posmoderno.
openaire   +3 more sources

A Multifaceted Interplay Among Hemophagocytosis, Interleukin‐18, and Type I Interferon Distinguishes Still Disease From Other Autoinflammatory Diseases

Arthritis &Rheumatology, EarlyView.
Objective The unknown pathophysiology and the lack of specific features for systemic juvenile idiopathic arthritis and adult‐onset Still disease (collectively known as Still disease; SD) delay diagnosis and appropriate treatment. The goal of this study was to identify features and mechanisms that distinguish SD from other systemic autoinflammatory ...
Yvonne M. Mueller, Charlotte Girard, Harmen J. G. van de Werken, Stefan J. Erkeland, Dwin G. B. Grashof, Laurie Vaillant, Renske J. H. den Dekker, Iris van Zuijen, Sharon Veenbergen, Fanny Coffin, Eric Bindels, Yvan Jamilloux, Katerina Laskari, Vassili Soumelis, Bruno Fautrel, Cem Gabay, Peter D. Katsikis   +16 more
wiley   +1 more source

The effects of long-term application of transcranial direct current stimulation on transfer of motor learning in Parkinson’s disease

Brain Stimulation, 2021
Milan Pantovic, Nickolas Pudar, Lidio Albuquerque, Desiree Morris, Sanne Broeder, Erik Wilkins, Merrill Landers, Zoltan Mari, Brach Poston   +8 more
doaj   +1 more source

Combination Therapy in Participants With Active Psoriatic Arthritis Using Subcutaneous Guselkumab and Golimumab: Week 24 Results From a Phase 2a, Multicenter, Randomized, Double‐Blind, Proof‐of‐Concept Study

Arthritis &Rheumatology, EarlyView.
Objective To assess guselkumab + golimumab combination therapy versus guselkumab monotherapy in participants with active psoriatic arthritis (PsA) and inadequate response to tumor necrosis factor inhibitors (TNFi‐IR). Methods Adults with active TNFi‐IR PsA (three or more tender/swollen joints) were randomized (2:1) to subcutaneous guselkumab (100 mg) +
Jose U. Scher, Iain B. McInnes, Enrique R. Soriano, Joseph F. Merola, Paul Bird, Vinod Chandran, Edaire Cheng, Elena Reynoso, Warner Chen, Maoji Li, Lianne S. Gensler, Philip J. Mease, Christopher T. Ritchlin   +12 more
wiley   +1 more source

A Novel Case of Biliary Atresia in a Premature Neonate With 1p36 Deletion Syndrome

Journal of Investigative Medicine High Impact Case Reports, 2018
We describe the case of a premature male neonate diagnosed with biliary atresia who was found to have chromosome 1p36 deletion syndrome. Our patient was born prematurely, at a gestational age of 28 weeks.
Vonita Chawla MD, Miran Rhee Anagnost MD, Alaa-Eldin Eldemerdash MD, Dahna Reyes MD, Rebecca Scherr MD, Kanayo Ezeanolue MD, Francis Banfro MD, Rabea Alhosh MD   +7 more
doaj   +1 more source

Fine Particulate Matter Constituents, Ozone, and Systemic Lupus Erythematosus: A Large General‐Population Cohort Analysis With Extended Quantile g‐Computation

Arthritis &Rheumatology, EarlyView.
Objective The aim of this study was to investigate whether exposure to mixture of individual fine particulate matter (PM2.5) chemical constituents is associated with incident systemic lupus erythematosus (SLE) and if ozone modifies this association and/or is associated with SLE onset.
Naizhuo Zhao, Sasha Bernatsky, Sharon Dowell, Brittany Banbury, Jeffrey R. Curtis, Grace C. Wright, Emily E. Holladay, Amy Mudano, Cristiano S. Moura, Gail S. Kerr   +9 more
wiley   +1 more source

Comparison of Metabolic and Pulmonary Variables Between Real-Life and Mixed Reality Pickleball

Journal of Functional Morphology and Kinesiology
Background: Pickleball is one of the fastest growing sports, and the use of virtual reality is also fast growing. Because the physiological responses in real life (IRL) vs.
Setareh Zarei, Matahn Blank, Jamaal Bovell, Dustin W. Davis, Jacob Baca, Michael W. H. Wong, Brett Abarbanel, James W. Navalta   +7 more
doaj   +1 more source

A man of his time: Joseph Leidy, racial science, and American anatomy

Anatomical Sciences Education, EarlyView.
Abstract Professor Joseph Leidy M.D. was arguably the most influential anatomist in the nineteenth‐century United States, having written over 500 publications and serving as the first President of the Association of American Anatomists. While many of Leidy's diverse contributions to American science and medicine are well‐known, scholars have said much ...
Christopher D. E. Willoughby
wiley   +1 more source

The Importance of Recruitment of Low-Income Pregnant Persons in Interdisciplinary Research to Understand the Impact of Social and Environmental Determinants: Lessons Learned About Implementation and Recruitment

Health Equity
Background: Prior research indicates that enrolling underrepresented populations in clinical research is challenging. Although research has identified some barriers to participation and strategies to overcome them, studies have made little progress in ...
Erika Marquez, Amanda Haboush-Deloye, Elizabeth Lawrence, Selam Ayele, Courtney Coughenour, Nora Doyle, Wynona Dizon, Lizbeth Perez Rodriguez, Chloe Bombara   +8 more
doaj   +1 more source