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Two Lasalocid Sodium Salts

Acta Crystallographica Section C Crystal Structure Communications, 1995
The structures of two new forms of lasalocid sodium salt, sodium 6-[7R-{5S-ethyl-5-(5R-ethyltetrahydro-5-hydroxy-6S-methyl-2H-pyran-2R-yl)tetrahydro-3S-methyl-2S-furanyl}-4S-hydroxy-3R,5S-dimethyl-6-oxononyl]-2-hydroxy-3-methylbenzoate (A), Na + .C 34 H 53 O 8 − , and sodium 6-[7R-{5S-ethyl-5-(5R-ethyltetrahydro-5-hydroxy-6S-methyl-2H-pyran-2R-yl ...
X. Shui, D. S. Eggleston
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Safety of lasalocid in turkeys and its compatibility with tiamulin

Veterinary Record, 1988
An investigation involving 640 turkeys demonstrated that the inclusion of lasalocid continuously from day-old to 16 weeks of age, at levels up to 375 ppm in the feed, produced no adverse effects; furthermore, the inclusion of 125 ppm lasalocid in the feed was compatible with the administration of 250 ppm tiamulin in the drinking water continuously for ...
N J, Lodge   +3 more
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Performance of beef heifers supplemented with sodium lasalocid

Tropical Animal Health and Production, 2016
This study was conducted on 78 13-month-old crossbred beef heifers that weighed 215 kg in Southern Rio Grande do Sul (RS) State, Brazil. We evaluated the performance of beef heifers that were reared in a pasture system that received a mineral supplement energy-type protein with added sodium lasalocid (LAS).
Everton Dezordi, Sartori   +5 more
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Evaluation of Lasalocid in Salt Against Ovine Coccidia

American Journal of Veterinary Research, 1981
SUMMARY Lasalocid at a level of 0.75% in free-choice granulated salt was highly efficacious against naturally acquired coccidia infections in lambs maintained in semiconfinement. Treated lambs consumed 18 g of medicated salt/day, reflecting an average daily lasalocid dosage of 4.3 mg/kg of body weight.
W J, Foreyt, N L, Gates, J E, Rich
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Effect of lasalocid, monensin and thiopeptin on rumen protozoa

Research in Veterinary Science, 1986
The effects of lasalocid, monensin and thiopeptin on the total number and the generic composition of rumen protozoa were determined in vivo and in vitro. Feeding lasalocid or monensin to cattle on either high grain or high roughage diets reduced total protozoal counts.
S M, Dennis, T G, Nagaraja, A D, Dayton
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Fitness of Amines for Pseudocyclic Conformation of Lasalocid A

Journal of Biomolecular Structure and Dynamics, 1995
Ionophore lasalocid A selectively transports amines across lipid membranes. The structures of amine-lasalocid complexes were calculated by a molecular mechanics technique. Four typical catecholamines were considered: serotonin, dopamine, noradrenaline and adrenaline.
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Potassium and Lasalocid Effects on Performance and Digestion in Lambs

Journal of Animal Science, 1986
Two trials were conducted to evaluate effects of dietary potassium (K) concentration and lasalocid (L) in lamb finishing diets. Treatments were arranged in a 2 X 2 factorial and consisted of a 65% concentrate diet with 1.1% K (C), .9% K + 21.3 mg L/kg (CL), 2.1% K (P) and 2.5% K + 20 mg L/kg (PL).
M A, Funk, M L, Galyean, T T, Ross
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The Total Synthesis of Lasalocid A

1980
A total asymmetric synthesis of the "right half ketone" of the stereo-complex polyether antibiotic, lasalocid A, is described. The [3,3] sigmatropic rearrangements of 0-silylketene acetals derived from esters of 1,4-anhydro-pent-1-enitols (furanoid glycals) and 1,5-anhydro-hex-1-enitols (pyranoid glycals) provided α-substituted-2,5-dihydrofuran-2 ...
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Prevention of Lactic Acidosis in Cattle by Lasalocid or Monensin

Journal of Animal Science, 1981
Intraruminal administration of lasalocid or monensin (1.3 mg/kg body weight) effectively prevented in glucose- or corn-induced lactic acidosis in cattle. Administering the antibiotics for 7 days before experimentally inducing acidosis with corn (27.5 g/kg body weight), effectively prevented acidosis, while 2 days' were sufficient to prevent glucose ...
T G, Nagaraja   +4 more
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Thermodynamic analysis of amines-lasalocid complex formation

Biophysical Chemistry, 1997
The ionophore lasalocid A selectively transports amines across lipid membranes. Free energy differences of amine-lasalocid complex formation reactions and the activation barriers of the complex transport were calculated by the finite difference thermodynamic integration method.
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